Recombinant mouse antibody to gp160(311-317). P3E1 recognized SF162gp140 and ΔV2gp140 equally and failed to recognize ΔV2ΔV3gp140 and ΔV3gp140. P3E1 neutralized SF162 efficiently.
Figure 1 Neutralization of tagged SF33 by anti-FLAG and anti-HA MAbs.
The neutralizing potentials of anti-FLAG and anti-HA MAbs against SF33 virions expressing WT or tagged Envs capable of mediating viral entry were evaluated.
Wallace, A., & Stamatatos, L. (2009). Introduction of exogenous epitopes in the variable regions of the human immunodeficiency virus type 1 envelope glycoprotein: effect on viral infectivity and the neutralization phenotype. Journal of virology, 83(16), 7883-7893.
Figure 2 SF33 Envs expressed on the cell surface were determined by fluorescence-activated cell sorting.
MAb 2G12 was used as a positive control; as a
negative control, we used cells expressing no Env (cells only).
Wallace, A., & Stamatatos, L. (2009). Introduction of exogenous epitopes in the variable regions of the human immunodeficiency virus type 1 envelope glycoprotein: effect on viral infectivity and the neutralization phenotype. Journal of virology, 83(16), 7883-7893.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-177) | WB, ELISA, Neut, FuncS | Human IgG |
PABL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 3H+109L) | WB, ELISA, FuncS | Human IgG |
PABL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128) | WB, ELISA, FuncS | Human IgG |
PABL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C) | WB, ELISA, Neut, FuncS | Human IgG, κ |
PABL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01) | FC, Neut, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBW-163 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 268-D); Fab Fragment | ELISA, Neut | Human Fab |
PSBL-551 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC16.01); scFv Fragment | Neut | Human scFv |
PSBL-552 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC18.02); scFv Fragment | Neut | Human scFv |
PSBL-553 | Human Anti-HIV-1 gp160 Recombinant Antibody; scFv Fragment (PSBL-553) | Neut | Human scFv |
MRO-4044CQ-S(P) | Rat Anti-HIV-1 gp160 Recombinant Antibody (clone 75); scFv Fragment | ELISA, IHC | Rat scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-086LC | Anti-HIV-1 gp160 Recombinant Antibody (1C1) | ELISA | Mouse antibody |
MRO-087LC | Anti-HIV-1 gp160 Recombinant Antibody (1H9) | ELISA | Mouse antibody |
MRO-086LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (1C1) | ELISA | Mouse antibody |
MRO-087LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (1H9) | ELISA | Mouse antibody |
MRO-088LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (2D7) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-075LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (24G3) | ELISA | Human antibody |
MRO-080LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (81C7) | ELISA | Human antibody |
MRO-091LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (MAb CL1) | ELISA | Human antibody |
MRO-100LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (N7019b) | ELISA | Human antibody |
MRO-101LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (K24-3b) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-3673CQ-F(E) | Chimpanzee Anti-HIV-1 gp160 Recombinant Antibody (clone C311E); Fab Fragment | Neut | Chimpanzee Fab |
MRO-3674CQ-F(E) | Human Anti-HIV-1 gp160 Recombinant Antibody (clone HGN35); Fab Fragment | ELISA | Human Fab |
MRO-3675CQ-F(E) | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10-188); Fab Fragment | ELISA, Neut | Human Fab |
MRO-3676CQ-F(E) | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10-380); Fab Fragment | Neut | Human Fab |
MRO-3677CQ-F(E) | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10J4); Fab Fragment | Neut | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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