This recombinant monoclonal antibody (Clone DH570.4) to HIV-1 gp41 is a Monkey monoclonal antibody that can be used for applications: ELISA, Neut.
Figure 1 Binding of DH570 lineage antibodies to MPER liposomes
Binding of DH570 antibodies were measured by Bio-layer Interferometry (BLI, ForteBio Octet Red96) following capture of MPER liposomes on APS sensors. Binding responses were monitored at varying concentrations of antibody at 3, 5, 20 ug/mL DH570.4.
Zhang, R., Verkoczy, L., Wiehe, K., Munir Alam, S., Nicely, N. I., Santra, S., ... & Haynes, B. F. (2016). Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Science translational medicine, 8(336), 336ra62-336ra62.
Figure 2 Neutralization of the DH570 clone
Neutralization curves and (D) summary table of IC50 and IC80 for DH570 and 2F5 against HIV isolate JRFL in the monocyte-derived macrophage neutralization assay
Zhang, R., Verkoczy, L., Wiehe, K., Munir Alam, S., Nicely, N. I., Santra, S., ... & Haynes, B. F. (2016). Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Science translational medicine, 8(336), 336ra62-336ra62.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-486 | Recombinant Anti-HIV-1 gp41 Antibody | WB, Dot, FuncS | IgG |
PABL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062) | WB, ELISA, FuncS | Human IgG |
PABL-186 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) | WB, Neut, FuncS | Human IgG |
PABL-187 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176) | Neut, FuncS | Human IgG |
PABL-188 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC315) | Neut, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-486-S(P) | Recombinant Anti-HIV-1 gp41 Antibody scFv Fragment | FC, WB, FuncS | scFv |
PSBC-331 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-331) | Neut | Mouse scFv |
PSBC-332 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8v4-5R+100cF); scFv Fragment | Neut | Human scFv |
PSBC-336 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-336) | ELISA, Neut | Mouse scFv |
PABJ-0083-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone VRC42.04); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBZ-068 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1583); Fab Fragment | Neut | Mouse Fab |
PFBW-068 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone D5); Fab Fragment | WB, ELISA | Human Fab |
PFBC-069 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone HK20); Fab Fragment | Neut, ELISA | Human Fab |
MRO-4045CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2-1007); Fab Fragment | ELISA | Human Fab |
MRO-4046CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 1-167); Fab Fragment | Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-074LC | Anti-HIV-1 gp41 Recombinant Antibody (W) | ELISA | Human antibody |
MRO-077LC | Anti-HIV-1 gp41 Recombinant Antibody (3D6) | ELISA | Human antibody |
MRO-079LC | Anti-HIV-1 gp41 Recombinant Antibody (3D9) | ELISA | Human antibody |
MRO-093LC | Anti-HIV-1 gp41 Recombinant Antibody (clone 43) | ELISA | Human antibody |
MRO-077LC-F(E) | Anti-HIV-1 gp41 Recombinant Antibody Fab Fragment (3D6) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC746 | A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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