Human Anti-HIV Tat Recombinant Antibody (clone tat31) (CAT#: FAMAB-0278JF)
This product is a recombinant monoclonal antibody (clone tat31) that specially binds to HIV-1 Tat. tat31 is a human monoclonal antibody that can be widely used in the treament of pateints with HIV-1 infection.
Specific Inquiry
ELISA
Figure 1 Retrospective analysis of anti-Tat antibody levels and p24 antigenemia in serial serum samples.
Trends of anti-Tat antibody levels and p24 antigenemia are shown over the entire observation period.
Re, M. C., Furlini, G., Vignoli, M., Ramazzotti, E., Roderigo, G., & De Rosa, V. (1995). Effect of Antibody to HIV-1 Tat Protein on Viral Replication in Vitro and Progression of HIV-1 Disease. Journal of acquired immune deficiency syndromes and human retrovirology, 10(4).
WB
Figure 2 Western blot analyses of HIV Tat protein, respectively, from transfected cell line.
A remarkable reduction of CAT activity in the presence of anti-Tat mAb.
Re, M. C., Furlini, G., Vignoli, M., Ramazzotti, E., Roderigo, G., & De Rosa, V. (1995). Effect of Antibody to HIV-1 Tat Protein on Viral Replication in Vitro and Progression of HIV-1 Disease. Journal of acquired immune deficiency syndromes and human retrovirology, 10(4).
IHC
Figure 3 Immunoreactivity of oligodendrocyte nuclei with anti-Tat antibody.
Original magnification ×100.
Del Valle, L., Croul, S., Morgello, S., Amini, S., Rappaport, J., & Khalili, K. (2000). Detection of HIV-1 Tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy. Journal of neurovirology, 6(3), 221-228.
FC
Figure 4 T-cell stimulation by Tat enhances histone acetylation and viral infection.
Tat stimulation of T cells for 24 h increases acetylated histone H3 in nuclear extracts.
Johnson, T. P., Patel, K., Johnson, K. R., Maric, D., Calabresi, P. A., Hasbun, R., & Nath, A. (2013). Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein. Proceedings of the National Academy of Sciences, 110(33), 13588-13593.
Specifications
- Immunogen
- HIV-1
- Host Species
- Human
- Derivation
- Human phage display Fab library
- Type
- Human IgG
- Specificity
- HIV Tat
- Species Reactivity
- HIV-1
- Clone
- tat31
- Applications
- WB, ELISA, IHC, FC
- Related Disease
- HIV-1 infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV Tat antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Flow Cytometry.
Target
- Alternative Names
- TAT; p14; Tat; Transactivating regulatory protein; HIV
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone tat31"
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-950 | Recombinant Anti-HIV tat Antibody | ELISA, WB, FuncS | IgG |
| MHH-950 | Recombinant Human Anti-HIV tat Antibody | WB, IF, FuncS | IgG |
| MRO-769CQ | Mouse Anti-HIV Tat Recombinant Antibody (clone AC11.AE12) | WB | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-950-F(E) | Recombinant Anti-HIV tat Antibody Fab Fragment | ELISA, FuncS | Fab |
| MHH-950-F(E) | Recombinant Human Anti-HIV tat Antibody Fab Fragment | WB, FC, FuncS | Fab |
| FAMAB-0278JF-F(E) | Human Anti-HIV Tat Recombinant Antibody (clone tat31); Fab Fragment | ELISA, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-950-S(P) | Recombinant Anti-HIV tat Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| MHH-950-S(P) | Recombinant Human Anti-HIV tat Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| FAMAB-0278JF-S(P) | Human Anti-HIV Tat Recombinant Antibody (clone tat31); scFv Fragment | ELISA, FuncS | Human scFv |
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B014(A) | Recombinant Anti-HIV-Tat Intrabody [(D-Arg)9] | FACS, ELISA, IF, FuncS | scFv-(D-Arg)9 |
| IAB-B014(G) | Recombinant Anti-HIV-Tat Intrabody [+36 GFP] | FACS, ICC, FuncS | scFv-(+36GFP) |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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