Rabbit Anti-HNRNPU Recombinant Antibody (clone R05-7N7) (CAT#: VS3-XY3383)

It is a recombinant rabbit antibody targeting the HNRNPU (Heterogeneous nuclear ribonucleoprotein U), which plays a role in the regulation of interphase large-scale gene-rich chromatin organization through chromatin-associated RNAs. It reacts with human, mouse and rat HNRNPU. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Flow cytometry, Immunocytochemistry or Immunofluorescence.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat HNRNPU
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R05-7N7
  • Applications
  • WB, IHC-P, ICC, IF, FC
  • Related Disease
  • Mitochondrial Complex Iv Deficiency, Nuclear Type 11

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IHC: 1/50-1/100
    IF: 1/50-1/200
    FC: 1/50-1/100

Target

  • Alternative Names
  • SAFA; DEE54; HNRPU; SAF-A; U21.1; pp120; EIEE54; GRIP120; hnRNP U; HNRNPU-AS1
  • Long Name
  • Heterogeneous nuclear ribonucleoprotein U
  • Cellular Localization
  • Nucleus, Chromosome, Cytoplasm, cytoskeleton
  • Post Translation Modifications
  • Citrullinated by PADI4. (Q00839-HNRPU_HUMAN)
    Ubiquitination at Lys9, Lys186, Lys265, Lys352, Lys464, Lys516, Lys524, Lys536, Lys544, Lys551, Lys565, Lys602, Lys635, Lys664, and Lys814 (NX_Q00839 [NX_Q00839-1])
    Modification sites at PhosphoSitePlus (Q00839)
    Glycosylation from GlyGen (Q00839) 8 sites, 1 O-linked glycan (7 sites)
  • Function
  • DNA- and RNA-binding protein involved in several cellular processes such as nuclear chromatin organization, telomere-length regulation, transcription, mRNA alternative splicing and stability, Xist-mediated transcriptional silencing and mitotic cell progression (PubMed:10490622, 18082603, 19029303, 22325991, 25986610, 28622508).
    Plays a role in the regulation of interphase large-scale gene-rich chromatin organization through chromatin-associated RNAs (caRNAs) in a transcription-dependent manner, and thereby maintains genomic stability.

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "HNRNPU"

Recombinant Antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1650 Rabbit Anti-HNRNPU Recombinant Antibody (clone DS1650AB) WB, IHC-P, ICC, IF Rabbit IgG

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for VS3-XY3383. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare