Recombinant Mouse Anti-HPV58 L1 Antibody (A12A3) (CAT#: PABC-529)
This product is a recombinant Mouse antibody that can recognize HPV58 L1. A12A3 specifically binds to and neutralizes HPV58. The epitopes of A12A3 are clustered in the DE loops of two adjacent HPV58 L1 monomers.
Specific Inquiry
ELISA
Figure 1 Binding of HPV58 pentamers to its type-specific neutralizing antibody A12A3.
Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.
ELISA
Figure 2 ELISA for evaluation of binding of chimeric VLPs of HPV33 against MAbs A12A3.
Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.
Neut
Figure 3 Neutralization assay of MAbs A12A3 to WT and mutant PsVs of HPV33.
Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.
Specifications
- Immunogen
- HPV58 and HPV59 VLPs
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- HPV58 L1
- Species Reactivity
- HPV58
- Clone
- A12A3
- Applications
- ELISA, Neut, WB
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay, Neutralization and Western Blot. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- Human Papillomavirus Type 58; HPV58; Human Papillomavirus Type 58 protein L1; HPV58 L1
- UniProt ID
- P26535
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-569LC | Anti-HPV58 L1 Recombinant Antibody (1A4) | ELISA | Mouse antibody |
| MRO-570LC | Anti-HPV58 L1 Recombinant Antibody (1C2) | ELISA | Mouse antibody |
| MRO-571LC | Anti-HPV58 L1 Recombinant Antibody (1D1) | ELISA | Mouse antibody |
| MRO-572LC | Anti-HPV58 L1 Recombinant Antibody (1D2) | ELISA | Mouse antibody |
| MRO-573LC | Anti-HPV58 L1 Recombinant Antibody (1G4) | ELISA | Mouse antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-529 | Recombinant Mouse Anti-HPV58 L1 Antibody Fab Fragment (A12A3) | ELISA, Neut, WB | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-529 | Recombinant Mouse Anti-HPV58 L1 Antibody scFv Fragment (A12A3) | ELISA, Neut, WB | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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