Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG2) (CAT#: HPAB-AP851-YC)
Provided are novel antibodies that specifically bind to an ORP150 polypeptide expressed of the cell surface of plasmacytoma, multiple myeloma, colorectal cancer cells, gastric cancer cells, or esophageal cancer cells. These antibodies can be used in a variety of diagnostic and therapeutic methods.
Specific Inquiry
FuncS
Figure 1 5F4 antibodies (c5F4-hIgG1, c5F4-hIgG2, c5F4-hIgG3, and c5F4-hIgG4) induced apoptosis of human plasmacytoma cell line U267 in vitro.
U266 cells were incubated with human Ig (a human Ig mixture, Scottish National Transfusion Service, Cat#F000685) or a chimeric 5F4 antibody at 1 ug/ml, 3 ug/ml, 10 ug/ml or 31 ug/ml in the presence of cross-linker (AffinityPure mouse anti-human IgG Fcγ
FuncS
Figure 2 Suppression of multiple myeloma tumor growth in SCID mice by a humanized 5F5 antibody.
Mice were implanted subcutaneously with L363 cells and treated intraperitoneally with humanized 5F4Ac.2/v17 or a control human IgG at 20 mg/kg three times weekly. Tumor volume was determined at day 5, 7, 9, 14, 16, 19, 21 and 24 after tumor implantation.
Specifications
- Immunogen
- The RPMI8226 cell membrane
- Host Species
- Human
- Type
- Human IgG2
- Specificity
- Human HYOU1
- Species Reactivity
- Human
- Clone
- c5F4-hIgG2
- Applications
- FuncS
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay.
Target
- Alternative Names
- Hypoxia Up-Regulated 1; 170 KDa Glucose-Regulated Protein; 150 KDa Oxygen-Regulated Protein; GRP-170; ORP-150; Grp170
- Gene ID
- 10525
- UniProt ID
- Q9Y4L1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone c5F4-hIgG2"
See other products for "HYOU1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1502CT | Recombinant Mouse anti-Human HYOU1 Monoclonal antibody (EML1057) | IHC-P, WB | |
| HPAB-0735-CN | Human Anti-HYOU1 Recombinant Antibody (clone h5F4Ac.2/v17) | WB, ELISA, IP, FC | Humanized IgG3, κ |
| HPAB-AP850-YC | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG1) | FuncS | Human IgG1 |
| HPAB-AP852-YC | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG3) | FuncS | Human IgG3 |
| HPAB-AP853-YC | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG4) | FuncS | Human IgG4 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1719 | Rabbit Anti-HYOU1 Recombinant Antibody (clone DS1719AB) | WB, IHC, ICC, IP | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-DJB-S(P) | Mouse Anti-HYOU1 Recombinant Antibody; scFv Fragment (HPAB-0007-DJB-S(P)) | ELISA, Apop | Mouse scFv |
| HPAB-0735-CN-S(P) | Human Anti-HYOU1 Recombinant Antibody (clone h5F4Ac.2/v17); scFv Fragment | WB, ELISA, IP, FC | Humanized scFv |
| HPAB-AP669-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 3B6.1); scFv Fragment | Apop, CDC, FC | Mouse scFv |
| HPAB-AP670-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 6A4.28); scFv Fragment | Apop, CDC, FC | Mouse scFv |
| HPAB-AP671-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 9A6.2); scFv Fragment | Apop, CDC, FC | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-DJB-F(E) | Mouse Anti-HYOU1 Recombinant Antibody; Fab Fragment (HPAB-0007-DJB-F(E)) | ELISA, Apop | Mouse Fab |
| HPAB-0735-CN-F(E) | Human Anti-HYOU1 Recombinant Antibody (clone h5F4Ac.2/v17); Fab Fragment | WB, ELISA, IP, FC | Humanized Fab |
| HPAB-AP669-YC-F(E) | Mouse Anti-HYOU1 Recombinant Antibody (clone 3B6.1); Fab Fragment | Apop, CDC, FC | Mouse Fab |
| HPAB-AP670-YC-F(E) | Mouse Anti-HYOU1 Recombinant Antibody (clone 6A4.28); Fab Fragment | Apop, CDC, FC | Mouse Fab |
| HPAB-AP671-YC-F(E) | Mouse Anti-HYOU1 Recombinant Antibody (clone 9A6.2); Fab Fragment | Apop, CDC, FC | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-AP851-YC. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.