This product is a Mouse antibody that recognizes IAV HA. Passive transfer of a murine IgG1 version of 8H10 conferred limited protection against 5xLD50 intranasal challenge of H3N2 X31, but the murine IgG2c version of 8H10 conferred complete protection against the same challenge regimen. An Fc-dependent mechanism was responsible for protection.
Figure 1 Mouse Anti-IAV HA Recombinant Antibody (clone 8H10) (PABJ-0096) in SDS-PAGE
SDS-PAGE analysis of PABJ-0096 in non-reduced (Lane 2) and reduced (Lane 1) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively. And non-reduced protein migrates as 130-180 kDa.
Figure 2 Mouse Anti-IAV HA Recombinant Antibody (clone 8H10) (PABJ-0096) in SEC-HPLC
HPLC analysis of PABJ-0096 shows the purity is>95%.
Figure 3 Human Anti-IAV H3N2 HA Recombinant Antibody (PABJ-0096) in WB
Western blot analysis of PABJ-0096 was performed with Recombinant Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin Protein (HA1 Subunit) (His Tag).
Lane 1: Reducing antigen (0.1 μg)
Lane 2: Reducing antigen (0.3 μg)
Lane 3: Reducing antigen (0.6 μg)
The secondary antibody: HRP Goat Anti-Human IgG (H+L)
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-078 | Recombinant Anti-IAV HA VHH Single Domain Antibody | FC, CA, IP, FuncS | Llama VHH |
HPAB-0344CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (HPAB-0344CQ) | ELISA, Neut | Llama VHH |
HPAB-0345CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (HPAB-0345CQ) | ELISA, Neut | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H33 | Anti-IAV HA Recombinant Antibody (Firivumab) | FC, IP, ELISA, Neut, FuncS, IF, ICC | IgG1 - kappa |
TAB-027ML | Anti-IAV HA Recombinant Antibody (Gedivumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
TAB-438CQ | Anti-IAV HA Recombinant Antibody (Navivumab) | ELISA, IHC, FC, IP, IF, BL | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-0652CQ | Recombinant Mouse Anti-IAV HA Antibody (pSAN13.4.1) | ELISA | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0190CQ | Recombinant Mouse Anti-IAV HA Antibody (FluBI) | ELISA, FC, Neut | Mouse IgG2b, κ |
FAMAB-0191CQ | Recombinant Mouse Anti-IAV HA Antibody (λαPR8-1) | ELISA | Mouse IgG |
FAMAB-0192CQ | Recombinant Mouse Anti-IAV HA Antibody (λαPR8-9) | ELISA | Mouse IgG |
HPAB-0680-CN | Human Anti-IAV HA Recombinant Antibody (HPAB-0680-CN) | ELISA, Neut | Human IgG |
HPAB-0681-CN | Human Anti-IAV HA Recombinant Antibody (HPAB-0681-CN) | ELISA, Neut | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0680-CN-F(E) | Human Anti-IAV HA Recombinant Antibody; Fab Fragment (HPAB-0680-CN-F(E)) | ELISA, Neut | Human Fab |
HPAB-0681-CN-F(E) | Human Anti-IAV HA Recombinant Antibody; Fab Fragment (HPAB-0681-CN-F(E)) | ELISA, Neut | Human Fab |
HPAB-0682-CN-F(E) | Human Anti-IAV HA Recombinant Antibody; Fab Fragment (HPAB-0682-CN-F(E)) | ELISA, Neut | Human Fab |
PFBC-343 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (6639) | ELISA, Neut | Human Fab |
PFBC-344 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (56.a.09) | ELISA, FC, Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-027ML | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Gedivumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
AFC-TAB-438CQ | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Navivumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
AFC-TAB-H33 | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Firivumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-YC213 | H-2Kd/Influenza A virus Haemagglutinin (IYSTVASSL) MHC Pentamer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0217WJ-S(P) | Human Anti-IAV HA Recombinant Antibody (clone FY5); scFv Fragment | ELISA, WB, Neut | Human scFv |
FAMAB-0218WJ-S(P) | Human Anti-IAV HA Recombinant Antibody (clone FY6); scFv Fragment | ELISA, WB, Neut | Human scFv |
FAMAB-0219WJ-S(P) | Human Anti-IAV HA Recombinant Antibody (clone 16D11); scFv Fragment | ELISA, WB, Neut | Human scFv |
FAMAB-0220WJ-S(P) | Human Anti-IAV HA Recombinant Antibody (clone 10B2); scFv Fragment | ELISA, WB, Neut | Human scFv |
PABJ-0204-S(P) | Human Anti-IAV HA Recombinant Antibody (clone FluA-20); scFv Fragment | ELISA, Inhib, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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