Mouse Anti-IGF1R Recombinant Antibody (clone 16-13) (CAT#: FAMAB-1169CQ)

This product is a recombinant mouse antibody that recognizes IGF1R. The antibody was purified by affinity chromatography. It can be used in IP, Stim.


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IP

Figure 1 Immunoprecipitation of biosynthetically labeled receptors.

Figure 1 Immunoprecipitation of biosynthetically labeled receptors.

IGF-lR/3T3 cells were biosynthetically labeled with [35S]methionine and chased for 10 h with unlabeled methionine. Cell lysates were immunoprecipitated with either a monoclonal antibody to the insulin receptor (83-14) or with the indicated IGF-I receptor antibodies. Immunoprecipitates were analyzed on 7.5% SDS-polyacrylamide gels, and an autoradiograph of the gel is shown. The positions of the molecular weight markers (in thousands), receptor precursor (αβ), andα-and β-subunits are indicated. Antibody 1-2 is anti-peptide monoclonal antibody against the C-terminal sequence of the type I IGF receptor.

Soos, M. A., Field, C. E., Lammers, R., Ullrich, A., Zhang, B., Roth, R. A., ... & Siddle, K. (1992). A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity. Journal of Biological Chemistry, 267(18), 12955-12963.


Specifications

  • Immunogen
  • Transfected cells expressing high levels of receptors (IGF-lR/3T3 cells)
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2b
  • Specificity
  • Human insulin-like growth factor 1 receptor (IGF1R)
  • Species Reactivity
  • Human
  • Clone
  • 16-13
  • Applications
  • IP, Stim

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Insulin Like Growth Factor 1 Receptor

Related Resources

  • Related Signaling Pathways
  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "IGF1R"

Recombinant Antibody

Humanized Antibody

Immunotoxin

CAT Product Name Application Type
AGTO-L024E IGF1-PE immunotoxin Cytotoxicity assay, Functional assay
AGTO-L024D IGF1-DT immunotoxin Cytotoxicity assay, Functional assay

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-371CL Afuco™ Anti-Human IGF1R Antibody, ADCC Enhanced (AFC-371CL) ELISA ADCC enhanced antibody
AFC-TAB-199 Afuco™ Anti-IGF1R Recombinant Antibody (AFC-TAB-199), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF Human IgG1, κ
AFC-TAB-209 Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Robatumumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-736 Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Dalotuzumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-078 Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Cixutumumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-084ZJ-F(E) Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-084ZJ-F(E)) ELISA, FC Chimeric (mouse/human) Fab
TAB-085ZJ-F(E) Anti-Human IGF-1R Recombinant Antibody Fab Fragment (6E11c) ELISA, Neut, FC, IHC Chimeric antibody (mouse/human)
TAB-086ZJ-F(E) Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-086ZJ-F(E)) ELISA, FC, Inhib, IP Chimeric (mouse/human) Fab
TAB-087ZJ-F(E) Anti-Human IGF-1R Recombinant Antibody Fab Fragment (ch7C2) ELISA Chimeric antibody (mouse/human)
TAB-093ZJ-F(E) Anti-Human IGF-1R Recombinant Antibody Fab Fragment (ch9E11) ELISA Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0103MZ Chicken Anti-CD221 Polyclonal IgY WB Chicken antibody

Neutralizing Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-1077CQ Mouse Anti-IGF1R Recombinant Antibody (clone 1H7) FC, Block, IHC, IP, WB Mouse IgG1, κ
NEUT-1078CQ Mouse Anti-IGF1R Recombinant Antibody (clone 24-60) Inhib, ICC, IF, IP, WB Mouse IgG2a, κ
NEUT-1079CQ Mouse Anti-IGF1R Recombinant Antibody (clone 17-69) Inhib, IP Mouse IgG1
NEUT-1080CQ Mouse Anti-IGF1R Recombinant Antibody (clone 24-57) Inhib, IP Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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