Rabbit Anti-IL13 Recombinant Antibody (clone R25-8A-1) (CAT#: VS3-FY2195)
This recombinant primary antibody, targeting human IL13, is a rabbit monoclonal. Western blot demonstrated that it recognized a target protein with a molecular weight of 16 kDa, with an observed molecular weight of 13 kDa. For western blot application, the recommended dilution range is 1/500 to 1/1000.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IL13
- Species Reactivity
- Human
- Clone
- R25-8A-1
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- The calculated weight of the target protein is approximately 16kDa, while the observed molecular weight stands at 13kDa.
- Related Disease
- Fibrotic and cancerous disorders
Product Property
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4), 150 mM NaCl, 50% glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Interleukin 13
- Gene ID
- 3596
- UniProt ID
- P35225
- Sequence Similarities
- Belongs to the IL-4/IL-13 family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Asn52, Asn63, Asn71, and Asn86 (NX_P35225 [NX_P35225-1])
Glycosylation from GlyGen (P35225) 4 sites
- Protein Refseq
- NP_001341920.1; NP_001341921.1; NP_001341922.1; NP_002179.2
- Function
- Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity).
Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (By similarity).
Functions also on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils.
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
Asthma
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IL13"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H05 | Anti-Human IL13 Recombinant Antibody (Anrukinzumab) | ELISA, Inhib | IgG1 |
| TAB-219 | Anti-Human IL13 Recombinant Antibody (Lebrikizumab) | ELISA, Neut, IF, IP, FC, FuncS | IgG4 - kappa |
| TAB-395CL | Human Anti-IL13 Recombinant Antibody (TAB-395CL) | FuncS | Human IgG |
| TAB-046ZJ | Human Anti-IL13 Recombinant Antibody (TAB-046ZJ) | ELISA, Block | Humanized IgG |
| PABX-115 | Recombinant Human Anti-IL-13 Antibody (C836) | WB, ELISA, FuncS | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-232 | Human Anti-IL13 Recombinant Antibody (clone M1295); scFv Fragment | WB, IHC, FuncS | Human scFv |
| HPAB-AP106-YC-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-AP106-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP107-YC-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-AP107-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP108-YC-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-AP108-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-0289-YJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-0289-YJ-S(P)) | ELISA, Neut, Inhib, FuncS | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-170 | Human Anti-IL13 Recombinant Antibody (clone CNTO607); Fab Fragment | ELISA, WB, Neut | Human Fab |
| HPAB-0226CQ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (HPAB-0226CQ-F(E)) | ELISA, Neut, FC, FuncS | Human Fab |
| HPAB-AP106-YC-F(E) | Mouse Anti-IL13 Recombinant Antibody; Fab Fragment (HPAB-AP106-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP107-YC-F(E) | Mouse Anti-IL13 Recombinant Antibody; Fab Fragment (HPAB-AP107-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP108-YC-F(E) | Mouse Anti-IL13 Recombinant Antibody; Fab Fragment (HPAB-AP108-YC-F(E)) | ELISA | Mouse Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022ZJ | Anti-Human IL-13 Recombinant Antibody (C836) | ELISA | |
| TAB-023ZJ | Mouse Anti-IL13 Recombinant Antibody (TAB-023ZJ) | ELISA, Block | Mouse IgG |
| TAB-022ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (C836) | ELISA | |
| TAB-023ZJ-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-023ZJ-S(P)) | ELISA, Block | Mouse scFv |
| TAB-022ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (C836) | ELISA |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-094ZJ | Anti-Human IL-13 Recombinant Antibody (167) | ELISA | Chimeric antibody (mouse/human) |
| TAB-094ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
| TAB-094ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-067ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (CNTO 607) | ELISA, Inhib | Human antibody |
| TAB-068ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (01471/G6) | ELISA, Neut | Human antibody |
| TAB-069ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-069ZJ-S(P)) | ELISA, Neut, FC | Human scFv |
| TAB-070ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-070ZJ-S(P)) | ELISA, Neut, FC | Human scFv |
| TAB-017ML | Anti-Human IL13 Recombinant Antibody (Dectrekumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0781CT | Recombinant Mouse anti-Human IL13 Monoclonal antibody (43227.22) | ELISA, Neut, WB | |
| HPAB-AP106-YC | Mouse Anti-IL13 Recombinant Antibody (HPAB-AP106-YC) | WB, ELISA, FC, IHC | Mouse IgG |
| HPAB-AP107-YC | Mouse Anti-IL13 Recombinant Antibody (HPAB-AP107-YC) | ELISA | Mouse IgG |
| HPAB-AP108-YC | Mouse Anti-IL13 Recombinant Antibody (HPAB-AP108-YC) | IHC, Inhib | Mouse IgG |
| HPAB-0286-YJ | Human Anti-IL13 Recombinant Antibody (HPAB-0286-YJ) | ELISA, Antagonist, FuncS | Human IgG1, κ |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1171CQ | Mouse Anti-IL13 Recombinant Antibody (clone B-B13) | ELISA, ELISPOT, Neut | Mouse IgG1 |
| NEUT-1172CQ | Mouse Anti-IL13 Recombinant Antibody (clone 10X28) | Neut, WB | Mouse IgG1 |
| NEUT-1173CQ | Mouse Anti-IL13 Recombinant Antibody (clone 15H10) | Neut | Mouse IgG2b |
| NEUT-1174CQ | Mouse Anti-IL13 Recombinant Antibody (clone 32116.11) | ELISA, Neut, WB | Mouse IgG1 |
| NEUT-1175CQ | Rat Anti-IL13 Recombinant Antibody (clone 5A2) | Neut | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1790 | Rabbit Anti-IL13 Recombinant Antibody (clone DS1790AB) | WB, ICC, FC, IP | Rabbit IgG |
| MOR-4610 | Rabbit Anti-IL13 Recombinant Antibody (clone TH123DS) | WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H05 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Anrukinzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-017ML | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Dectrekumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| AFC-TAB-219 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Lebrikizumab), ADCC Enhanced | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
| AFC-TAB-218 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Tralokinumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-FY2195. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.