Recombinant Human Anti-IV HA Antibody (CH65) (CAT#: HPAB-0387-WJ)

This product is a humanized antibody CH65 that specifically binds to influenza hemagglutinin. CH65 reduces or inhibits hemagglutinin binding to sialic acid.


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ELISA

Figure 1 ELISA reactivity of the indicated antibodies with wild-type HA from A/New Caledonia/20/1999 (H1 wt), H1 containing Arg substitutions that blocks access to the stem epitope, H1 delta stem (I45R/T49R), and H1 with an N-glycan insertion that also prevents access to the stem epitope, H1 delta stem (45glyc).

Figure 1 ELISA reactivity of the indicated antibodies with wild-type HA from A/New Caledonia/20/1999 (H1 wt), H1 containing Arg substitutions that blocks access to the stem epitope, H1 delta stem (I45R/T49R), and H1 with an N-glycan insertion that also prevents access to the stem epitope, H1 delta stem (45glyc).

Nandin, I. S., Fong, C., Deantonio, C., Torreno-Pina, J. A., Pecetta, S., Maldonado, P., ... & Borley, D. W. (2017). Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies. Journal of Experimental Medicine, 214(8), 2471-2490.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Human IgG
  • Specificity
  • Influenza hemagglutinin
  • Species Reactivity
  • Influenza virus
  • Clone
  • CH65
  • Applications
  • ELISA
  • Related Disease
  • Influenza

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • Hemagglutinin; HA; haemagglutinin

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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