Human Anti-IVIG Recombinant Antibody (clone LO10) (CAT#: FAMAB-0032JF)
Recombinant human monoclonal can specially bind to IVIG. This anti-IVIG antibody (LO10) can be poteincially used in autoimmune diseases study.
Specific Inquiry
Inhib
Figure 1 Intravenous immunoglobulin (IVIG) inhibits immune-mediated demyelination in organotypic cerebellar slice culture (OSC).
OSC were treated as indicated and green fluorescent protein (GFP)-expression was assessed in living OSC using a fluorescence microscope 1 and 2 days after the induction of demyelination.
Winter, M., Baksmeier, C., Steckel, J., Barman, S., Malviya, M., Harrer‐Kuster, M., ... & Goebels, N. (2016). Dose‐dependent inhibition of demyelination and microglia activation by IVIG. Annals of clinical and translational neurology, 3(11), 828-843.
IHC
Figure 2 Representative confocal images: IVIG preserves the myelin sheath around axons.
Values are depicted as mean ± SEM.
Winter, M., Baksmeier, C., Steckel, J., Barman, S., Malviya, M., Harrer‐Kuster, M., ... & Goebels, N. (2016). Dose‐dependent inhibition of demyelination and microglia activation by IVIG. Annals of clinical and translational neurology, 3(11), 828-843.
WB
Figure 3 Ig-variable regions do not mediate intravenous immunoglobulin (IVIG)-mediated inhibition of demyelination.
Polyclonal Fab fragments were generated from whole IVIG by papain cleavage.
Winter, M., Baksmeier, C., Steckel, J., Barman, S., Malviya, M., Harrer‐Kuster, M., ... & Goebels, N. (2016). Dose‐dependent inhibition of demyelination and microglia activation by IVIG. Annals of clinical and translational neurology, 3(11), 828-843.
ELISA
Figure 4 ELISA measurements of specific anti-tau antibodies in IVIG products.
Data shown are means ± SDs from data from six experiments.
Smith, L. M., Coffey, M. P., Klaver, A. C., & Loeffler, D. A. (2013). Intravenous immunoglobulin products contain specific antibodies to recombinant human tau protein. International Immunopharmacology, 16(4), 424-428.
Specifications
- Host Species
- Human
- Derivation
- Human phage display Fab library
- Type
- Human IgG
- Specificity
- Human IVIG
- Species Reactivity
- Human
- Clone
- LO10
- Applications
- WB, ELISA, IHC, Inhib
- Related Disease
- Autoimmune thrombocytopenic purpura
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IVIG antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Inhibition.
Target
- Alternative Names
- Intravenous immunoglobulins; IVIG
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone LO10"
See other products for "IVIG"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592 | Recombinant Anti-IVIG Antibody | ELISA, IP, FuncS | IgG |
| MHH-592 | Recombinant Human Anti-IVIG Antibody | RIA, WB, FuncS | IgG |
| VS-0423-CJ16 | Human Anti-IVIG Recombinant Antibody (clone mg30b) | ELISA | Human IgG |
| VS-0423-CJ17 | Human Anti-IVIG Recombinant Antibody (clone mg29a) | ELISA | Human IgG |
| VS-0423-CJ18 | Human Anti-IVIG Recombinant Antibody (clone mg14b) | ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592-F(E) | Recombinant Anti-IVIG Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| MHH-592-F(E) | Recombinant Human Anti-IVIG Antibody Fab Fragment | ELISA, WB, Neut, FuncS | Fab |
| FAMAB-0032JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone LO10); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0033JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone GGb-04); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0034JF-F(E) | Human Anti-IVIG Recombinant Antibody (clone NK07); Fab Fragment | WB, ELISA, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-592-S(P) | Recombinant Anti-IVIG Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| MHH-592-S(P) | Recombinant Human Anti-IVIG Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| FAMAB-0032JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone LO10); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0033JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone GGb-04); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0034JF-S(P) | Human Anti-IVIG Recombinant Antibody (clone NK07); scFv Fragment | WB, ELISA, FuncS | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-0032JF. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.