Rabbit Anti-KDM4B Recombinant Antibody (clone R08-9G9) (CAT#: VS3-FY1756)
This marvelous recombinant antibody is crucial for validating in immunohistochemistry (IHC) studies. As a rabbit recombinant monoclonal antibody that is designed to target human KDM4B. It is suitable for use in a variety of assays, including WB, IHC-F, IHC-P, ICC/IF. This R08-9G9 antibody is validated for western blot analysis of KDM4B in 293, COS7 lysates.
Specific Inquiry
WB
Figure 1 Anti-KDM4B Antibody (VS3-FY1756) in WB.
The KDM4B expression in 293, COS7 lysates were detected using the anti-KDM4B by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human KDM4B/JMJD2B
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human KDM4B
- Species Reactivity
- Human
- Clone
- R08-9G9
- Applications
- Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence
- MW
- The calculated weight of the target protein is approximately 122 kDa, while the observed molecular weight stands at 150 kDa.
- Related Disease
- Intellectual Developmental Disorder, Autosomal Dominant 65 and Non-Specific Syndromic Intellectual Disability
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunofluorescence: 1/50-1/200
Target
- Alternative Names
- Lysine Demethylase 4B; JmjC Domain-Containing Histone Demethylation Protein 3B; Jumonji Domain-Containing Protein 2B; Lysine (K)-Specific Demethylase 4B; Jumonji Domain Containing 2B; Tudor Domain Containing 14B; JMJD2B
- Gene ID
- 23030
- UniProt ID
- O94953
- Sequence Similarities
- Belongs to the JHDM3 histone demethylase family.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Acetylation
Phosphoprotein
- Protein Refseq
- XP_005259578.2; XP_011526116.1; XP_011526119.1; XP_011526121.1; XP_011526122.1
- Function
- Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "KDM4B"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-376 | Recombinant Human Anti-Human KDM4B Antibody, clone D437 | ELISA, IP-MS | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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