Human Anti-KREMEN2 Recombinant Antibody (clone hSC78.56sslMJ) (CAT#: HPAB-N0361-YC)
Provided are novel anti-KREMEN2 antibodies, which can be used to treat cancer.
Specific Inquiry
FuncS
Figure 1 KREMEN2 antibody drug conjugates produce durable remissions in lung squamous cell carcinoma, breast, and ovarian cancer PDX-bearing mice.
FuncS
Figure 2 KREMEN2 antibody drug conjugates effectively deplete cancer stem cell populations in lung squamous cell carcinoma PDX tumors.
Specifications
- Immunogen
- hKREMEN2 protein
- Host Species
- Human
- Derivation
- Humanized
- Type
- Human IgG1, κ (C220S, N297A)
- Specificity
- Human KREMEN2
- Species Reactivity
- Human
- Clone
- hSC78.56sslMJ
- Applications
- ELISA, FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Functional Assay. Please see the Published Data for further information.
Target
- Alternative Names
- Kringle Containing Transmembrane Protein 2; Kringle-Containing Protein Marking The Eye And The Nose; Kringle Domain-Containing Transmembrane Protein 2; Dickkopf Receptor 2; KRM2; Kremen Protein 2
- Gene ID
- 79412
- UniProt ID
- Q8NCW0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1974 | Hi-Affi™ Recombinant Rabbit Anti-KREMEN2 Monoclonal Antibody (DS1974AB) | WB | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0360-YC | Mouse Anti-KREMEN2 Recombinant Antibody (clone SC78.56) | ELISA, FC, FuncS | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0360-YC-S(P) | Mouse Anti-KREMEN2 Recombinant Antibody (clone SC78.56); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-N0361-YC-S(P) | Human Anti-KREMEN2 Recombinant Antibody (clone hSC78.56sslMJ); scFv Fragment | ELISA, FC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0360-YC-F(E) | Mouse Anti-KREMEN2 Recombinant Antibody (clone SC78.56); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-N0361-YC-F(E) | Human Anti-KREMEN2 Recombinant Antibody (clone hSC78.56sslMJ); Fab Fragment | ELISA, FC | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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