Human Anti-LAMA3 Recombinant Antibody (clone ch1H12) (CAT#: HPAB-0804-CN)
This is a chimeric antibody derived from murine antibody 1H12, which binds to the LG4-5 domain of chain α3 of human protein laminin-5. Monoclonal antibody ch1H12 inhibits the binding of syndecan-1 to laminin-5 α3 chain LG4-5 domain.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/45_E2_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/45_E2_1_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10757/953_G12_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10757/953_G12_1_selected.jpg
Figure 3 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/ihc_selected.jpg
Figure 4 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10757/40984_A_5_2_selected.jpg
(Immunohistochemical staining of human small intestine shows strong cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10757/40984_A_5_2_selected.jpg
Figure 5 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/25209_B_8_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/25209_B_8_5.jpg
Figure 6 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranou)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/25209_A_9_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranou)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/25209_A_9_3.jpg
Figure 7 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/25209_A_8_4.jpg
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/25209_A_8_4.jpg
Figure 8 Testis
(Cells in seminiferous ducts
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10757/40984_A_5_6.jpg
(Cells in seminiferous ducts
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10757/40984_A_5_6.jpg
Figure 9 Lymph node
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/25209_A_8_8.jpg
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9309/25209_A_8_8.jpg
Figure 10 RNA cell line category: Cell line enriched (HBEC3-KT)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053747-LAMA3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053747-LAMA3
Specifications
- Immunogen
- Purified recombinant LG4/5
- Host Species
- Human
- Derivation
- Human
- Type
- Chimeric (mouse/human) IgG1, κ
- Species Reactivity
- Human
- Clone
- ch1H12
- Applications
- WB, ELISA
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone ch1H12"
See other products for "LAMA3"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2772z | Mouse Anti-LAMA3 Recombinant Antibody (clone 44A8) | WB, FC, ICC, IHC, IP | Mouse IgG1 |
| HPAB-0803-CN | Mouse Anti-LAMA3 Recombinant Antibody (clone 1H12) | WB, ELISA | Mouse IgG1, κ |
| HPAB-0805-CN | Human Anti-LAMA3 Recombinant Antibody (clone hu1H12) | WB, ELISA | Humanized IgG1, κ |
| MRO-0915-CN | Recombinant Rabbit Anti-LAMA3 Monoclonal Antibody (JJ0957) | WB, IF | Rabbit IgG |
| HPAB-J0161-YC | Mouse Anti-LAMA3 Recombinant Antibody (HPAB-J0161-YC) | FuncS | Mouse IgG1, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1677CQ | Recombinant Mouse Anti-LAMA3 Antibody (P3H9-2) | BL, WB, IP, ICC, IHC | IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0803-CN-S(P) | Mouse Anti-LAMA3 Recombinant Antibody (clone 1H12); scFv Fragment | WB, ELISA | Mouse scFv |
| HPAB-0804-CN-S(P) | Human Anti-LAMA3 Recombinant Antibody (clone ch1H12); scFv Fragment | WB, ELISA | Human scFv |
| HPAB-0805-CN-S(P) | Human Anti-LAMA3 Recombinant Antibody (clone hu1H12); scFv Fragment | WB, ELISA | Human scFv |
| HPAB-J0161-YC-S(P) | Mouse Anti-LAMA3 Recombinant Antibody; scFv Fragment (HPAB-J0161-YC-S(P)) | ELISA, Inhib, FuncS | Mouse scFv |
| HPAB-J0162-YC-S(P) | Mouse Anti-LAMA3 Recombinant Antibody; scFv Fragment (HPAB-J0162-YC-S(P)) | ELISA, Inhib, FuncS | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0803-CN-F(E) | Mouse Anti-LAMA3 Recombinant Antibody (clone 1H12); Fab Fragment | WB, ELISA | Mouse Fab |
| HPAB-0804-CN-F(E) | Human Anti-LAMA3 Recombinant Antibody (clone ch1H12); Fab Fragment | WB, ELISA | Human Fab |
| HPAB-0805-CN-F(E) | Human Anti-LAMA3 Recombinant Antibody (clone hu1H12); Fab Fragment | WB, ELISA | Human Fab |
| HPAB-J0161-YC-F(E) | Mouse Anti-LAMA3 Recombinant Antibody; Fab Fragment (HPAB-J0161-YC-F(E)) | ELISA, Inhib, FuncS | Mouse Fab |
| HPAB-J0162-YC-F(E) | Mouse Anti-LAMA3 Recombinant Antibody; Fab Fragment (HPAB-J0162-YC-F(E)) | ELISA, Inhib, FuncS | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0804-CN. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.