Rabbit Anti-LGMN Recombinant Antibody (clone R06-7G1) (CAT#: VS3-FY1758)
The R06-7G1 antibody has been teted by western blot. Legumain antibody detected positive in western blot analysis of legumain in Jurkat, Hela lysates. The recombinant monoclonal antibody demonstrated a greater affinity with human LGMN.
Specific Inquiry
WB
Figure 1 Anti-LGMN Antibody (VS3-FY1758) in WB.
The Legumain expression in Jurkat, Hela lysates were detected using the anti-Legumain by western blot assay.
Specifications
- Immunogen
- Recombinant human Legumain protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human LGMN
- Species Reactivity
- Human
- Clone
- R06-7G1
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 49 kDa, while the observed molecular weight stands at 56,46,37 kDa.
- Related Disease
- Aneruptive Fever and Cerebral Amyloid Angiopathy, Cst3-Related
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- AEP; LGMN1; PRSC1
- Gene ID
- 5641
- UniProt ID
- Q99538
- Sequence Similarities
- Belongs to the peptidase C13 family.
- Cellular Localization
- Lysosome
- Post Translation Modifications
- Activated by autocatalytic processing at pH 4.
- Protein Refseq
- XP_005267919.1; XP_005267920.1; XP_011535272.1; XP_016876952.1; XP_047287551.1
- Function
- Can also cleave aspartyl bonds slowly, especially under acidic conditions.
Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol (By similarity).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "LGMN"
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2047 | Hi-Affi™ Recombinant Rabbit Anti-LGMN Monoclonal Antibody (DS2047AB) | WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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