Human Anti-LILRB4 Recombinant Antibody (clone h128-3); Fab fragment (CAT#: PABJ-0128-F(E))
This product is a Human antibody Fab fragment that recognizes Human LILRB4. MAb h128-3 showed potent activity in blocking development of monocytic AML in various models including patient-derived xenograft (PDX) mice and syngeneic immunocompetent AML mice. MAb h128-3 enhanced the anti-AML efficacy of chemotherapy treatment by stimulating mobilization of leukemia cells.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186818-LILRB4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186818-LILRB4
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human LILRB4
- Species Reactivity
- Human
- Clone
- h128-3
- Applications
- ELISA, Block, ADCC
- Related Disease
- Acute myeloid leukemia
Product Property
- Purification
- Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Blocking, Antibody-dependent cellular cytotoxicity.
Target
- Alternative Names
- ILT3; LIR5; CD85K; ILT-3; LIR-5; leukocyte immunoglobulin-like receptor subfamily B member 4; CD85 antigen-like family member K; immunoglobulin-like transcript 3; leucocyte Ig-like receptor B4; leukocyte immunoglobulin-like receptor 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; monocyte inhibitory receptor HM18
- Gene ID
- 11006
- UniProt ID
- Q8NHJ6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single-domain Antibody
Mouse Antibody
Chimeric Antibody
Humanized Antibody
Recombinant Antibody
scFv Fragment Antibody
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1298-VHH | Recombinant Anti-Human LILRB4 VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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