Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
  • Home
  • LMAN1
  • Rabbit Anti-LMAN1 Recombinant Antibody (clone R01-8R1)

Rabbit Anti-LMAN1 Recombinant Antibody (clone R01-8R1) (CAT#: VS3-XY3418)

It is a recombinant rabbit antibody targeting the LMAN1 (Lectin, mannose binding 1), which may recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors. It recognizes and binds to human LMAN1. It also has cross-reactivity against mouse and rat LMAN1. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence.


See more Engineered Antibody products for LMAN1
Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line EFO-21
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/2063_G6_7_selected.jpg
Figure 2 IHC staining of human duodenum
Figure 2 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity with granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2320/ihc_selected.jpg
Figure 3 IHC staining of human breast
Figure 3 IHC staining of human breast
(Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/85396_B_8_5.jpg
Figure 5 Thyroid gland
Figure 5 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/85396_B_3_5.jpg
Figure 6 Colon
Figure 6 Colon
(Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/85396_A_9_3.jpg
Figure 7 Liver
Figure 7 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/85396_A_8_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/85396_A_9_5.jpg
Figure 9 Testis
Figure 9 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Sertoli cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/85396_A_6_6.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37163/85396_A_9_8.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000074695-LMAN1

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat LMAN1
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R01-8R1
  • Applications
  • WB, IHC-P, ICC, IF
  • Related Disease
  • Factor V And Factor Viii, Combined Deficiency of, 2

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IHC: 1/50-1/100
    IF: 1/50-1/200

Target

  • Alternative Names
  • MR60; gp58; F5F8D; FMFD1; MCFD1; ERGIC53; ERGIC-53
  • Long Name
  • Lectin, mannose binding 1
  • Cellular Localization
  • Golgi apparatus membrane, Endoplasmic reticulum membrane
  • Post Translation Modifications
  • The N-terminal may be partly blocked. (P49257-LMAN1_HUMAN)
    Glycosylation at Thr276, Thr385, Ser425, Thr432, and Thr433 (NX_P49257 [NX_P49257-1])
    Ubiquitination at Lys346 and Lys372 (NX_P49257 [NX_P49257-1])
    Modification sites at PhosphoSitePlus (P49257)
    Glycosylation from GlyGen (P49257) 9 sites, 5 O-linked glycans (9 sites)
  • Function
  • Mannose-specific lectin.
    May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both.
    The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.

Recommended Products

Isotype Control

Recommended Dilution Buffer

Secondary Antibody

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "LMAN1"

Recombinant Antibody

CAT Product Name Application Type
MOB-2385z Mouse Anti-LMAN1 Recombinant Antibody (clone 15A2) WB, FC, ICC, IF, IHC Mouse IgG1
VS3-FY849 Recombinant Rabbit Anti-LMAN1 Antibody (clone R03-5C3) WB, IHC-P Rabbit IgG

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0324MZ Chicken Anti-LMAN1 Polyclonal IgY WB Chicken antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2065 Hi-Affi™ Recombinant Rabbit Anti-LMAN1 Monoclonal Antibody (DS2065AB) WB, IHC, ICC IgG

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for VS3-XY3418. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart
    Inquiry

    Go to compare