Human mAb S20 binds only to P. aeruginosa 06ad LPS O-side-chain PS and not to LPS O-side-chain PSs from other strains. S20 is effective at fixing complement to the bacterial surface.
Figure 1 Blocking of the binding of human anti-LPS MAb S20 to solid-phase P. aeruginosa strain 06ad LPS O-side-chain PS in an ELISA.
The x axis shows micrograms of 06ad PS or control PS per milliliter added to each reaction tube. The y axis depicts the percent reduction of absorbance obtained with the PS inhibitor.
Hemachandra, S., Kamboj, K., Copfer, J., Pier, G., Green, L. L., & Schreiber, J. R. (2001). Human monoclonal antibodies against Pseudomonas aeruginosa lipopolysaccharide derived from transgenic mice containing megabase human immunoglobulin loci are opsonic and protective against fatal pseudomonas sepsis. Infection and immunity, 69(4), 2223-2229.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-630 | Recombinant Anti-LPS Antibody | ELISA, WB, FC, FuncS | IgG |
MHH-630 | Recombinant Human Anti-LPS Antibody | WB, IP, FuncS | IgG |
PABL-078 | Recombinant Mouse Anti-E. coli LPS Antibody (WN1 222-5) | WB, ELISA, FuncS | IgG |
PABC-178 | Recombinant Mouse Anti-F. tularensis LPS Antibody (Ab52) | WB | IgG |
HPAB-0235-FY | Recombinant Human Anti-LPS Antibody (1774) | WB, E | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-630-F(E) | Recombinant Anti-LPS Antibody Fab Fragment | IF, FACS, FuncS | Fab |
MHH-630-F(E) | Recombinant Human Anti-LPS Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
HPAB-0422-WJ-F(E) | Recombinant Mouse Anti-LPS Antibody Fab Fragment (2459) | ELISA, FC | Mouse Fab |
HPAB-0423-WJ-F(E) | Recombinant Mouse Anti-LPS Antibody Fab Fragment (2409) | ELISA, FC | Mouse Fab |
HPAB-0424-WJ-F(E) | Recombinant Mouse Anti-LPS Antibody Fab Fragment (2453) | ELISA, FC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NABL-060 | Recombinant Anti-V. cholerae O1 LPS VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBC-178 | Recombinant Mouse Anti-F. tularensis LPS Antibody Fab Fragment (Ab52) | WB | Fab |
HPAB-0422-WJ-S(P) | Recombinant Mouse Anti-LPS Antibody scFv Fragment (2459) | ELISA, FC | Mouse scFv |
HPAB-0423-WJ-S(P) | Recombinant Mouse Anti-LPS Antibody scFv Fragment (2409) | ELISA, FC | Mouse scFv |
HPAB-0424-WJ-S(P) | Recombinant Mouse Anti-LPS Antibody scFv Fragment (2453) | ELISA, FC | Mouse scFv |
HPAB-J0169-YC-S(P) | Recombinant Human Anti-LPS Antibody scFv Fragment (216-01) | ELISA, FuncS | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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