Afuco™ Anti-LTA ADCC Recombinant Antibody (Pateclizumab), ADCC Enhanced (CAT#: AFC-TAB-071)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to TNF beta. Pateclizumab is an immunomodulator. It binds to lymphotoxin alpha.
Specific Inquiry
SEC-HPLC
Figure 1 Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) in HPLC
The purity of AFC-TAB-071 was greater than 95% as determined by SEC-HPLC.
Lectin WB
Figure 2 Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) in Lectin WB
Western blot analysis of AFC-TAB-071 was performed and fucose was detected by AOL-Biotin and SA-HRP. The result was negative, which indicates that there is no fucose produced.
Lane 1: Reducing AFC-TAB-071 (2 μg)
Lane 2: Reducing mouse anti-human IgG (2 μg)
Lectin ELISA
Figure 3 Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) in Lectin ELISA
Lectin ELISA analysis of AFC-TAB-071 was conducted and fucose was detected using AOL-Biotin and SA-HRP
The result indicates that there is almost no fucose produced.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Pateclizumab
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Generic Name
- Pateclizumab
- Related Disease
- Rheumatoid arthritis (RA)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Pateclizumab; 1202526-59-7; Anti-LTa; RG7416; MLTA3698A; PRO283698; LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1;
- Gene ID
- 4049
- UniProt ID
- P01374
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Pateclizumab"
Anti-Human TNF beta Recombinant Antibody (Pateclizumab)Recombinant monoclonal antibody to TNF beta. Pateclizumab is an immunomodulator. It binds to lymphotoxin alpha.
See other products for "LTA"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2017-sdAb | Recombinant Anti-LTA VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-071 | Anti-Human TNF beta Recombinant Antibody (Pateclizumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 - kappa |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-266 | Human Anti-LTA Recombinant Antibody; scFv Fragment | WB, IHC, FuncS | Human scFv |
| PSBL-630 | Human Anti-LTA Recombinant Antibody (clone MLTΑ3698A); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0024LY-S(P) | Human Anti-LTA Antibody scFv Fragment (AVP-V-7-27) | WB | scFv |
| HPAB-1246WJ-S(P) | Recombinant Human Anti-LTA Antibody scFv Fragment (A120) | ELISA | scFv |
| HPAB-2080-FY-S(P) | Mouse Anti-LTA Recombinant Antibody (clone 96-110); scFv Fragment | ELISA | Mouse scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-635 | Human Anti-LTA Recombinant Antibody (clone MLTΑ3698A) | ELISA, FC | Human IgG |
| MOB-2067CT | Recombinant Mouse anti-Human LTA Monoclonal antibody (460-92-22) | FC | |
| HPAB-0024LY | Recombinant Human Anti-LTA Antibody (AVP-V-7-27) | WB | |
| HPAB-1246WJ | Recombinant Human Anti-LTA Antibody (A120) | ELISA | Chimeric (human/mouse) IgG |
| HPAB-2080-FY | Mouse Anti-LTA Recombinant Antibody (clone 96-110) | ELISA | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-630 | Human Anti-LTA Recombinant Antibody (clone MLTΑ3698A); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0209-YC-F(E) | Human Anti-LTA Recombinant Antibody (clone ch2C8); Fab Fragment | ELISA, FC, Block | Human Fab |
| HPAB-0210-YC-F(E) | Human Anti-LTA Recombinant Antibody (clone ch3F12); Fab Fragment | ELISA, FC, Block | Human Fab |
| HPAB-0024LY-F(E) | Human Anti-LTA Antibody Fab Fragment (AVP-V-7-27) | WB | Fab |
| HPAB-2080-FY-F(E) | Mouse Anti-LTA Recombinant Antibody (clone 96-110); Fab Fragment | ELISA | Mouse Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-275CQ-S(P) | Human Anti-LTA Recombinant Antibody; scFv Fragment (TAB-275CQ-S(P)) | ELISA, FC, WB | Mouse scFv |
| TAB-275CQ-F(E) | Human Anti-LTA Recombinant Antibody; Fab Fragment (TAB-275CQ-F(E)) | ELISA, FC, WB | Chimeric (mouse/human) Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1702CQ | Recombinant Mouse Anti-LTA Antibody (359-238-8) | ELISA(Cap), ELISpot, Neut | IgG1, κ |
| NEUT-1703CQ | Recombinant Human Anti-LTA Antibody (3F12.2D3) | Neut, ELISA, FC | IgG1, κ |
| NEUT-1704CQ | Recombinant Mouse Anti-LTA Antibody (CBL411) | ICC, Neut | IgG1 |
| NEUT-1705CQ | Recombinant Mouse Anti-LTA Antibody (CBL412) | ELISA(Cap), Neut | IgG2a |
| NEUT-1706CQ | Recombinant Mouse Anti-LTA Antibody (MM0575-7U9) | Neut, IHC, IHC-P | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2097 | Hi-Affi™ Recombinant Rabbit Anti-LTA Monoclonal Antibody (DS2097AB) | WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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