Rabbit Anti-MBNL1 Recombinant Antibody (clone R02-4E4) (CAT#: VS3-FY2028)
The anti-MBNL1 antibody applied to western blot analysis of MBNL1 in A549, HL-60, U251 lysates. This marvelous rabbit recombinant monoclonal antibody that has been genetically engineered to specifically target human MBNL1.
Specific Inquiry
WB
Figure 1 Anti-MBNL1 Antibody (VS3-FY2028) in WB.
The MBNL1 expression in A549, HL-60, U251 lysates were detected using the anti-MBNL1 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human MBNL1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MBNL1
- Species Reactivity
- Human
- Clone
- R02-4E4
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 42 kDa, while the observed molecular weight stands at 42 kDa.
- Related Disease
- Myotonic Dystrophy and Corneal Dystrophy, Fuchs Endothelial, 3
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Muscleblind Like Splicing Regulator 1; Triplet-Expansion RNA-Binding Protein; MBNL; EXP; Muscleblind-Like Splicing Regulator 1; Muscleblind (Drosophila)-Like
- Gene ID
- 4154
- UniProt ID
- Q9NR56
- Sequence Similarities
- Belongs to the muscleblind family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Ubiquitination at Lys12 and Lys41 (NX_Q9NR56 [NX_Q9NR56-1])
Modification sites at PhosphoSitePlus (Q9NR56)
Glycosylation from GlyGen (Q9NR56) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_005247515.1; XP_005247518.1; XP_047304091.1; XP_047304092.1; XP_047304093.1
- Function
- Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MBNL1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2391CT | Recombinant Mouse anti-Human MBNL1 Monoclonal antibody (FQS2494) | ELISA, WB |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2183 | Hi-Affi™ Recombinant Rabbit Anti-MBNL1 Monoclonal Antibody (DS2183AB) | WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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