Recombinant Camelid Anti-MRC1 Single Domain Antibody (CAT#: HPAB-0924WJ)

This product is a single domain Single Domain Antibody targeting mouse MRC1. This Single Domain Antibody can be used in the field of cancer diagnostics and therapeutics and monitoring of the disease.


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ELISA

Figure 1 PE-ELISA on human MMR. Summary of the selected anti-human MMR Nb clones.

Figure 1 PE-ELISA on human MMR. Summary of the selected anti-human MMR Nb clones.

A clone was selected when the OD405nm was at least 3 times higher on specific antigen as compared to irrelevant milk blocking proteins.

ELISA

Figure 2 Shows the selected anti-human/mouse MMR cross-reactive Nb clones by ELISA.

Figure 2 Shows the selected anti-human/mouse MMR cross-reactive Nb clones by ELISA.

A clone was selected when the OD405nm was at least 3 times higher on specific antigen as compared to irrelevant milk blocking proteins.

PP

Figure 3 Purification of a number of selected Nb clones.

Figure 3 Purification of a number of selected Nb clones.

Coomassie stained 12% SDS-PAGE gel loaded with protein fractions after IMAC purification of NbhmMMRm5.38 periplasmic extract.

SPR

Figure 4 Surface Plasmon resonance sensograms of NbhmMMRm3.49 binding to recombinant human and mouse MMR.

Figure 4 Surface Plasmon resonance sensograms of NbhmMMRm3.49 binding to recombinant human and mouse MMR.

NbhmMMRm3.49 was injected in multiple concentrations at 30 μΙ/min.

FC

Figure 5 MMR specific Nbs bind to mouse MMR expressed on ex vivo isolated macrophages.

Figure 5 MMR specific Nbs bind to mouse MMR expressed on ex vivo isolated macrophages.

FC

Figure 6 Nbs bind to human MMR expressed on induced dendritic cells.

Figure 6 Nbs bind to human MMR expressed on induced dendritic cells.

Anti-hMMR Nbs bind to CDllc+ subsets in human iDC single-cell suspensions. Shaded histograms depict binding of the negative control Nb BCII10.


Specifications

  • Host Species
  • Camelid
  • Derivation
  • Phage display library
  • Type
  • Camelid VHH
  • Specificity
  • Mouse MRC1
  • Species Reactivity
  • Mouse
  • Applications
  • ELISA, PP, SPR, FC
  • Related Disease
  • Cancers

Applications

  • Application Notes
  • The MRC1 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Protein Purification, Surface Plasmon Resonance, Flow Cytometry.

Target

  • Alternative Names
  • MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "MRC1"

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MOB-672-F(E) Recombinant Anti-human MRC1 Antibody Fab Fragment RIA, ELISA, FuncS Fab
MHH-672-F(E) Recombinant Human Anti-human MRC1 Antibody Fab Fragment WB, ELISA, IHC, FuncS Fab

scFv Fragment Antibody

Single-domain Antibody

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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