Rabbit Anti-MUC5AC Recombinant Antibody (clone R05-4H2) (CAT#: VS3-XY3439)
This product is a recombinant rabbit antibody targeting the human MUC5AC (Mucin 5AC, oligomeric mucus/gel-forming). It recognizes and binds to human MUC5AC. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Western Blot, Immunohistochemistry-Paraffin and Immunofluorescence is 1/500-1/1000, 1/50-1/100 and 1/50-1/200, respectively.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in stomach 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_6_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_6_1_val_selected.jpg
Figure 2 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_9_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_9_4_val_selected.jpg
Figure 3 Stomach
(Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_3_1.jpg
(Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_3_1.jpg
Figure 4 RNA cell line category: Group enriched (A549, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215182-MUC5AC
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215182-MUC5AC
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MUC5AC
- Species Reactivity
- Human
- Clone
- R05-4H2
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Dry Eye Syndrome; Biliary Tract Disease
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- TBM; leB; MUC5; mucin
- Gene ID
- 4586
- UniProt ID
- P98088
- Long Name
- Mucin 5AC, oligomeric mucus/gel-forming
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Asn205, Asn258, Asn415, Asn524, Asn1308, Trp1389, Trp1584, Trp1749, Trp1957, Trp2122, Thr2395, Thr2405, Thr2451, Thr2461, Thr2531, Thr2541, Thr2571, Thr2581, Thr2699, Thr2709, Thr2883, Thr2893, Thr2979, Thr2989, Thr3067, Thr3077, Trp3228, Trp3526, Asn3774, Trp3959, Thr4224, Thr4234, Thr4296, Thr4306, Thr4320, Thr4330, Thr4376, Thr4386, Thr4440, Thr4450, Thr4480, Thr4490, Thr4512, Thr4522, Thr4568, Thr4578, Trp4633, Asn4869, Asn4942, Asn5057, Asn5093, Asn5236, Asn5347, Asn5377, Asn5386, Asn5455, Asn5528, and Asn5591 (NX_P98088 [NX_P98088-1])
Glycosylation from GlyConnect MUC5A_HUMAN (375)
Glycosylation from GlyGen (P98088) 63 sites, 17 O-linked glycans (1 site)
- Protein Refseq
- NP_001291288.1
- Function
- Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system.
Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD).
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MUC5AC"
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-200 | Anti-Human MUC5AC Recombinant Antibody (Ensituximab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-404MZ | Mouse Anti-MUC5AC Recombinant Antibody (TAB-404MZ) | ELISA, Inhib, IHC, IA | Mouse IgG |
| TAB-404MZ-S(P) | Mouse Anti-MUC5AC Recombinant Antibody; scFv Fragment (TAB-404MZ-S(P)) | IHC | Mouse scFv |
| TAB-404MZ-F(E) | Mouse Anti-MUC5AC Recombinant Antibody; Fab Fragment (TAB-404MZ-F(E)) | IHC | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-405MZ | Human Anti-MUC5AC Recombinant Antibody (TAB-405MZ) | IF, WB, IHC, IA | Humanized IgG |
| TAB-406MZ | Anti-Human MUC5AC Recombinant Antibody (VH-1) | FC, ELISA | Humanized antibody |
| TAB-405MZ-S(P) | Human Anti-MUC5AC Recombinant Antibody; scFv Fragment (TAB-405MZ-S(P)) | IHC | Humanized scFv |
| TAB-406MZ-S(P) | Anti-Human MUC5AC Recombinant Antibody scFv Fragment (VH-1) | FC, ELISA | Humanized antibody |
| TAB-405MZ-F(E) | Human Anti-MUC5AC Recombinant Antibody; Fab Fragment (TAB-405MZ-F(E)) | IHC | Humanized Fab |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0585CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (19-O Le) | ELISA | IgM |
| EPAF-0586CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (2-25 Le) | ELISA | IgG1 |
| EPAF-0587CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (7 Le) | ELISA | IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340LY-S(P) | Mouse Anti-MUC5AC Recombinant Antibody (clone 58-1066); scfv Fragment | ELISA | Mouse scfv |
| HPAB-AP150-YC-S(P) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1); scFv Fragment | ELISA, Cyt | Human scFv |
| HPAB-AP151-YC-S(P) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10); scFv Fragment | ELISA, Cyt | Human scFv |
| HPAB-0566-YJ-S(P) | Mouse Anti-MUC5AC Recombinant Antibody; scFv Fragment (HPAB-0566-YJ-S(P)) | WB, ELISA, Inhib, IP, IHC, FuncS | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340LY-F(E) | Mouse Anti-MUC5AC Recombinant Antibody (clone 58-1066); Fab Fragment | ELISA | Mouse Fab |
| HPAB-AP150-YC-F(E) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1); Fab Fragment | ELISA, Cyt | Human Fab |
| HPAB-AP151-YC-F(E) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10); Fab Fragment | ELISA, Cyt | Human Fab |
| HPAB-0566-YJ-F(E) | Mouse Anti-MUC5AC Recombinant Antibody; Fab Fragment (HPAB-0566-YJ-F(E)) | WB, ELISA, Inhib, IP, IHC, FuncS | Mouse Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-200 | Afuco™ Anti-MUC5AC ADCC Recombinant Antibody (Ensituximab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1061 | PE-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1062 | APC-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1063 | FITC-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1064 | B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP150-YC | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1) | ELISA, Cyt | Human IgG |
| HPAB-AP151-YC | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10) | ELISA, Cyt | Human IgG |
| MOB-0116F | Mouse Anti-MUC5AC Recombinant Antibody (MOB-0116F) | IHC-P, IF | Mouse IgG |
| MOB-0117F | Mouse Anti-MUC5AC Recombinant Antibody (MOB-0117F) | IHC-P, IF | Mouse IgG |
| VS3-WK138 | Mouse Anti-MUC5AC Recombinant Antibody (clone G6-H8) | WB, ELISA | Mouse IgG2a |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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