Human Anti-N. meningitidis Recombinant Antibody (clone LUNm01) (CAT#: FAMAB-0091WJ)

This product is a human monoclonal antibody reacts with the class 5c outer membrane protein commonly found among pathogenic strains of N. meningitidis.


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ELISA

Figure 1 The specificity of the antibodies secreted by these two stable hybridomas was investigated by blocking ELISA.

Figure 1 The specificity of the antibodies secreted by these two stable hybridomas was investigated by blocking ELISA.

LuNm01 and LuNm03 bound to the same or to closely related epitopes, as evident by their mutual blocking capabilities.

Fernández de Cossío, M. E., Ohlin, M., Llano, M., Selander, B., Cruz, S., del Valle, J., & Borrebaeck, C. A. (1992). Human monoclonal antibodies against an epitope on the class 5c outer membrane protein common to many pathogenic strains of Neisseria meningitidis. The Journal of infectious diseases, 166(6), 1322–1328.

WB

Figure 2 Reaction of monoclonal antibodies with OMP (treated at I00℃) on Western blot.

Figure 2 Reaction of monoclonal antibodies with OMP (treated at I00℃) on Western blot.

Lane A, mouse anti-class I antibody C6; lane B, control human anti-cytomegalovirus pp65 antibody. Lanes C, D, recognition of 31-kDa antigen (numbers at left) by human antibodies LuNmOI and LuNm03, respectively.

Fernández de Cossío, M. E., Ohlin, M., Llano, M., Selander, B., Cruz, S., del Valle, J., & Borrebaeck, C. A. (1992). Human monoclonal antibodies against an epitope on the class 5c outer membrane protein common to many pathogenic strains of Neisseria meningitidis. The Journal of infectious diseases, 166(6), 1322–1328.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, κ
  • Species Reactivity
  • N. meningitidis
  • Clone
  • LUNm01
  • Applications
  • ELISA, WB

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • N. meningitidis; Meningococcus

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Recombinant Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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