Human Anti-N. meningitidis Recombinant Antibody (clone LUNm03) (CAT#: FAMAB-0092WJ)

This product is a human monoclonal antibody reacts with the class 5c outer membrane protein commonly found among pathogenic strains of N. meningitidis. The isotype of this antibody is human IgG3, kappa.


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ELISA

Figure 1 The specificity of the antibodies secreted by these two stable hybridomas was investigated by blocking ELISA.

Figure 1 The specificity of the antibodies secreted by these two stable hybridomas was investigated by blocking ELISA.

Blocking ofbinding ofmouse anti-class 5c antibody A222/5b and B306, respectively, by human monoclonal antibodies to class 5c protein.

Fernández de Cossío, M. E., Ohlin, M., Llano, M., Selander, B., Cruz, S., del Valle, J., & Borrebaeck, C. A. (1992). Human monoclonal antibodies against an epitope on the class 5c outer membrane protein common to many pathogenic strains of Neisseria meningitidis. The Journal of infectious diseases, 166(6), 1322–1328.

WB

Figure 2 Reaction of antibodies with purified class 5c protein (lane A) and OMP preparation (lanes B-E), illustrating comigration of class 5c protein with antigen recognized by LuNm03.

Figure 2 Reaction of antibodies with purified class 5c protein (lane A) and OMP preparation (lanes B-E), illustrating comigration of class 5c protein with antigen recognized by LuNm03.

Epitope detected by LuNm03 (lane D) comigrated with class 5c protein, although signal is substantially fainter than that with murine antibody.

Fernández de Cossío, M. E., Ohlin, M., Llano, M., Selander, B., Cruz, S., del Valle, J., & Borrebaeck, C. A. (1992). Human monoclonal antibodies against an epitope on the class 5c outer membrane protein common to many pathogenic strains of Neisseria meningitidis. The Journal of infectious diseases, 166(6), 1322–1328.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG3, κ
  • Species Reactivity
  • N. meningitidis
  • Clone
  • LUNm03
  • Applications
  • ELISA, WB

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • N. meningitidis; Meningococcus

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone LUNm03"

See other products for "N. meningitidis"

Recombinant Antibody

CAT Product Name Application Type
MOB-696 Recombinant Anti-N. meningitidis Antibody ELISA, WB, IP, FuncS IgG
MHH-696 Recombinant Human Anti-N. meningitidis Antibody ELISA, IF, FuncS IgG
PABL-282 Mouse Anti-N. meningitidis Recombinant Antibody (PABL-282) WB, IHC, FuncS Mouse IgG
MRO-782-MZ Anti-N. meningitidis Polyclonal Antibody ELISA, ICC/IF, WB Rabbit antibody
MRO-783-MZ Anti-N. meningitidis Polyclonal Antibody (Biotin) ELISA, Dot blot, ICC/IF, ICC Rabbit antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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