Mouse Anti-PRKAG1 Recombinant Antibody (clone 5A1) (CAT#: VS3-WK1592)
This antibody is a mouse recombinant antibody against human PRKAG1, which is one of the gamma regulatory subunits of AMPK. The clone 5A1 can be used in IHC analysis at a dilution of 1/50-1/200.
Specific Inquiry
Specifications
- Immunogen
- Synthesized peptide derived from human AMPK γ1
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human PRKAG1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- 5A1
- Applications
- IHC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 0.5% BSA, 50% Glycerol
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- IHC: 1/50-1/200
Target
- Alternative Names
- AMPKG
- Gene ID
- 5571
- UniProt ID
- P54619
- Long Name
- Protein kinase AMP-activated non-catalytic subunit gamma 1
- Sequence Similarities
- Belongs to the 5'-AMP-activated protein kinase gamma subunit family.
- Cellular Localization
- Cytosol, Nucleoplasm, Nucleus
- Post Translation Modifications
- Phosphorylated by ULK1 and ULK2; leading to negatively regulate AMPK activity and suggesting the existence of a regulatory feedback loop between ULK1, ULK2 and AMPK.
- Protein Refseq
- NP_001193638.1; NP_001193639.1; NP_002724.1
- Function
- AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "PRKAG1"
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2849 | Hi-Affi™ Recombinant Rabbit Anti-PRKAG1 Monoclonal Antibody (DS2849AB) | FC, ICC, IHC-P, IP, WB | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1302 | Mouse Anti-PRKAG1 Recombinant Antibody (clone 4A1G9) | IHC | Mouse IgG1 |
| VS3-XY1303 | Mouse Anti-PRKAG1 Recombinant Antibody (clone 7H3E9) | IHC, ICC | Mouse IgG1 |
| VS3-FY1648 | Rabbit Anti-PRKAG1 Recombinant Antibody (clone R08-7D5) | WB, IP | Rabbit IgG |
| VS3-WK1593 | Mouse Anti-PRKAG1 Recombinant Antibody (clone 5H5) | IHC-P, WB | Mouse IgG |
| VS3-WK1596 | Mouse Anti-PRKAG1 Recombinant Antibody (clone 3G12) | IHC-P, WB | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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