Rabbit Anti-PSMA6 Recombinant Antibody (clone R01-4I2) (CAT#: VS3-FY1855)

Clone R01-4I2 is a rabbit recombinant monoclonal antibody that exhibits specific binding to human PSMA6. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, ICC/IF. This proteasome alpha 6 antibody was verified by western blot analysis of proteasome subunit alpha type 6 in K562, C6, 3T3, Hela lysates.


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WB

Figure 1 Anti-PSMA6 Antibody (VS3-FY1855) in WB.

Figure 1 Anti-PSMA6 Antibody (VS3-FY1855) in WB.

The Proteasome subunit alpha type 6 expression in K562, C6, 3T3, Hela lysates were detected using the anti-Proteasome alpha 6 by western blot assay.


Specifications

  • Immunogen
  • Synthetic peptide of human proteasome alpha subunit type 6
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat PSMA6
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R01-4I2
  • Applications
  • Western Blot, Immunofluorescence
  • MW
  • The calculated weight of the target protein is approximately 27 kDa, while the observed molecular weight stands at 27 kDa.
  • Related Disease
  • Myocardial Infarction and Combined Oxidative Phosphorylation Deficiency 8

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunofluorescence: 1/50-1/200

Target

  • Alternative Names
  • IOTA; p27K; PROS27
  • Sequence Similarities
  • Belongs to the peptidase T1A family.
  • Cellular Localization
  • Cytoplasm, Nucleus, Proteasome
  • Post Translation Modifications
  • Glycosylation at Ser5 (NX_P60900 [NX_P60900-1])
    Ubiquitination at Lys102, Lys104, Lys45, Lys30, Lys55, Lys116, Lys59, Lys164, Lys171, and Lys181 (NX_P60900 [NX_P60900-1])
    Modification sites at PhosphoSitePlus (P60900)
    Glycosylation from GlyGen (P60900) 2 sites, 1 O-linked glycan (1 site)
  • Function
  • The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "PSMA6"

Recombinant Antibody

CAT Product Name Application Type
MOB-3033z Mouse Anti-PSMA6 Recombinant Antibody (clone 1B12) WB, IHC Mouse IgG1

Rabbit Monoclonal Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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