Rabbit Anti-PTGDS Recombinant Antibody (clone R06-1C5) (CAT#: VS3-FY1853)

This is a rabbit recombinant monoclonal antibody that with high affinity for human PTGDS. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, IHC-F, IHC-P, ICC/IF.
Applications Tested: This antbody has been tested by western blot analysis of prostaglandin D synthase in K562, C6, 3T3, Hela lysates.
Immunohistochemistry analysis of paraffin-embedded human lung cancer tissue using prostaglandin D synthase antibody.


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WB

Figure 1 Anti-PTGDS Antibody (VS3-FY1853) in WB.

Figure 1 Anti-PTGDS Antibody (VS3-FY1853) in WB.

The Prostaglandin D Synthase expression in K562, C6, 3T3, Hela lysates were detected using the anti-Prostaglandin D Synthase by western blot assay.

IHC

Figure 2 Anti-PTGDS Antibody (VS3-FY1853) in IHC.

Figure 2 Anti-PTGDS Antibody (VS3-FY1853) in IHC.

Immunohistochemistry staining of paraffin-embedded human lung cancer tissue using the anti-Prostaglandin D Synthase antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.


Specifications

  • Immunogen
  • Synthetic peptide of human prostaglandin D synthase
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat PTGDS
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R06-1C5
  • Applications
  • Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence
  • MW
  • The calculated weight of the target protein is approximately 21 kDa, while the observed molecular weight stands at 26 kDa.
  • Related Disease
  • Human lung cancer

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunohistochemistry: 1/50-1/100
    Immunofluorescence: 1/50-1/200

Target

  • Alternative Names
  • PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS
  • Sequence Similarities
  • Belongs to the calycin superfamily. Lipocalin family.
  • Cellular Localization
  • Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Membrane, Nucleus, Secreted
  • Post Translation Modifications
  • N- and O-glycosylated.
    Both N-glycosylation recognition sites are almost quantitatively occupied by N-glycans of the biantennary complex type, with a considerable proportion of structures bearing a bisecting GlcNAc.
  • Function
  • Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "PTGDS"

Fab Fragment Antibody

CAT Product Name Application Type
DrMAB-1066 Recombinant Mouse Anti-Human PTGDS Antibody Fab Fragment ELISA Fab

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2916 Hi-Affi™ Recombinant Rabbit Anti-PTGDS Monoclonal Antibody (DS2916AB) WB, IHC-P, ICC/IF IgG

Recombinant Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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