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  • Mouse Anti-RAB29 Recombinant Antibody (VS3-CJ133)

Mouse Anti-RAB29 Recombinant Antibody (VS3-CJ133) (CAT#: VS3-CJ133)

This product is a mouse antibody that recognizes RAB29.


See more Engineered Antibody products for RAB29
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Subcellular Location
Figure 1 IF staining of human cell line HDLM-2
Figure 1 IF staining of human cell line HDLM-2
(Immunofluorescent staining of human cell line HDLM-2 shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26303/1959_C2_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human adrenal gland
Figure 2 IHC staining of human adrenal gland
(Immunohistochemical staining of human adrenal gland shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26303/55137_B_4_5_selected.jpg
Figure 3 IHC staining of human colon
Figure 3 IHC staining of human colon
(Immunohistochemical staining of human colon shows moderate positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20822/46847_A_8_3_selected.jpg
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26303/55137_B_8_5.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26303/55137_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26303/55137_A_5_6.jpg
Figure 7 Skin
Figure 7 Skin
(Keratinocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Langerhans Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Melanocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26303/55137_B_8_1.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117280-RAB29

Specifications

  • Immunogen
  • Recombinant protein of human RAB7L1
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Human RAB29
  • Species Reactivity
  • Human
  • Applications
  • WB
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Protein G affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • This antibody has been tested for use in Western Blot (1:1000).

Target

  • Alternative Names
  • Ras-related protein Rab-7L1; Rab-7-like protein 1; Ras-related protein Rab-29; RAB29; RAB7L1
  • Sequence Similarities
  • Belongs to the small GTPase superfamily. Rab family.
  • Cellular Localization
  • Cell membrane, Cytoplasm, Cytoskeleton, Golgi apparatus, Membrane, Vacuole
  • Post Translation Modifications
  • In case of Salmonella enterica serovar Typhimurium (S.Typhimurium) infection, is proteolytically cleaved between Gly-41 and Val-42 by the GtgE viral protease encoded on the Gifsy-2 lysogen bacteriophage, which therefore prevents the recruitment of RAB29 to S.Typhimurium-containing vacuoles. In contrast, no proteolytically cleavage is detected in S.Typhi-infected cells (PubMed:22042847).
  • Function
  • The small GTPases Rab are key regulators in vesicle trafficking (PubMed:24788816).
    Essential for maintaining the integrity of the endosome-trans-Golgi network structure (By similarity).
    Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner (PubMed:24788816).
    Recruits LRRK2 to the Golgi complex and stimulates LRRK2 kinase activity (PubMed:29212815).
    Regulates neuronal process morphology in the intact central nervous system (CNS) (By similarity).
    May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection (PubMed:22042847).

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "RAB29"

Recombinant Antibody

CAT Product Name Application Type
MOB-1194CT Recombinant Mouse anti-Human RAB7L1 Monoclonal antibody (EML877) WB

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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