Rabbit Anti-RAD23A Recombinant Antibody (clone R06-7H6) (CAT#: VS3-FY2009)

The R06-7H6 recombinant monoclonal antibody exhibits specific detecting to human RAD23A. It cross-reacts with mouse. It is suitable for use in a variety of assays, including WB, IP. This hHR23A antibody has been rigorously validated and is widely used in western blot analysis of hHR23A in 3T3 lysates.


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WB

Figure 1 Anti-RAD23A Antibody (VS3-FY2009) in WB.

Figure 1 Anti-RAD23A Antibody (VS3-FY2009) in WB.

The hHR23A expression in 3T3 lysates were detected using the anti-hHR23A by western blot assay.


Specifications

  • Immunogen
  • Synthetic peptide of human hHR23A
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human and Mouse RAD23A
  • Species Reactivity
  • Human, Mouse
  • Clone
  • R06-7H6
  • Applications
  • Western Blot, Immunoprecipitation
  • MW
  • The calculated weight of the target protein is approximately 40 kDa, while the observed molecular weight stands at 52 kDa.
  • Related Disease
  • Xeroderma Pigmentosum, Variant Type and Xeroderma Pigmentosum, Complementation Group C

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
  • Preservative
  • 0.01% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunoprecipitation: 1/20

Target

  • Alternative Names
  • RAD23 Homolog A, Nucleotide Excision Repair Protein; RAD23, Yeast Homolog, A; HHR23A; HR23A; UV Excision Repair Protein RAD23 Homolog A; RAD23 (S. Cerevisiae) Homolog A; RAD23 Homolog A (S. Cerevisiae)
  • Sequence Similarities
  • Belongs to the RAD23 family.
  • Cellular Localization
  • Nucleus, Proteasome
  • Post Translation Modifications
  • Ubiquitination at Lys8, Lys16, Lys26, Lys53, Lys78, Lys80, and Lys122 (NX_P54725 [NX_P54725-1])
    Modification sites at PhosphoSitePlus (P54725)
    Glycosylation from GlyGen (P54725) 3 sites, 1 O-linked glycan (3 sites)
  • Function
  • Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "RAD23A"

Rabbit Monoclonal Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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