Rabbit Anti-RNGTT Recombinant Antibody (clone R06-6B2) (CAT#: VS3-FY1735)

The R06-6B2 recombinant monoclonal antibody shows a high affinity for human RNGTT. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, IP. The specificity of the HCE antibody was confirmed by western blot analysis of HCE in K562, C6, 3T3 lysates.


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WB

Figure 1 Anti-RNGTT Antibody (VS3-FY1735) in WB.

Figure 1 Anti-RNGTT Antibody (VS3-FY1735) in WB.

The HCE expression in K562, C6, 3T3 lysates were detected using the anti-HCE by western blot assay.


Specifications

  • Immunogen
  • Recombinant human HCE protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat RNGTT
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R06-6B2
  • Applications
  • Western Blot, Immunoprecipitation
  • MW
  • The calculated weight of the target protein is approximately 69 kDa, while the observed molecular weight stands at 69 kDa.
  • Related Disease
  • Lymphomatous Meningitis and Cecum Adenocarcinoma

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunoprecipitation: 1/20

Target

  • Alternative Names
  • RNA Guanylyltransferase And 5'-Phosphatase; RNA Guanylyltransferase And 5-Phosphatase; HCAP1; CAP1A; HCE; MRNA-Capping Enzyme; HCAP; HCE1
  • Cellular Localization
  • Nucleus
  • Function
  • Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "RNGTT"

Recombinant Antibody

CAT Product Name Application Type
MOB-2806z Mouse Anti-RNGTT Recombinant Antibody (clone 36G8) WB, ELISA, IF, IP Mouse IgG1, κ
VS3-WK1316 Mouse Anti-RNGTT Recombinant Antibody (VS3-WK1316) ELISA, WB Mouse IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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