Recombinant Mouse Antibody clone RBC11, which is specific to Ricin B chain. This antibody recognizes Ricinus communis ricin toxin B chain.
Figure 1 In vitro neutralization of ricin by polyclonal horse Fab preparations and MAbs.
Panel A. Agilent microcapillary electrophoresis of intact monoclonal RTAs, MAb against RTA (RAC18 IgG vs. RAC18 Fab), and the polyclonal horse anti-ricin "Fab" preparation, under reducing and non-reducing conditions. The horse antibody preparation consists primarily of F(ab)'2 fragments. Panel B. ELISA binding of antibodies to plates coated with RT. Different secondary enzyme-conjugated antibodies were used to detect the horse and mouse Igs. Antibody concentration represents total protein. For MAbs, 100% is RT-specific antibody, whereas for the horse Fab, only 3.2% is RT specific. Panel C. In vitro neutralization of RT cytotoxicity by intact antibody and Fab fragments. Antibody concentration represents total protein. No antibody and control antibodies yield identical curves. Panel D. In vitro neutralization by high titer antibodies against RTA, (RAC), RTB (RBC), or both. Antibodies were used at 10 µg/mL.
Pincus, S. H., Smallshaw, J. E., Song, K., Berry, J., & Vitetta, E. S. (2011). Passive and active vaccination strategies to prevent ricin poisoning. Toxins, 3(9), 1163-1184.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NABL-030 | Recombinant Anti-RTB VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0295CQ-F(E) | Mouse Anti-RTB Recombinant Antibody (clone RBC11); Fab Fragment | ELISA, IF | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0295CQ-S(P) | Mouse Anti-RTB Recombinant Antibody (clone RBC11); scFv Fragment | ELISA, IF | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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