Human Anti-SARS-CoV Recombinant Antibody (clone 03-018) (CAT#: HPAB-1912-FY)
This product is a recombinant antibody that recognizes SARS-CoV. The monoclonal antibody 03-018 reacts with the epitope of SARS-CoV.
Specific Inquiry
ELISA
Figure 1 Selective binding of isolated scFv phage antibodies to SARS-CoV by ELISA.
Phage produced from individual colonies were analyzed for binding to SARS-CoV or FBS coated on microtiter wells.
van den Brink, E. N., ter Meulen, J., Cox, F., Jongeneelen, M. A., Thijsse, A., Throsby, M., ... & Martina, B. E. (2005). Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acuratory syndrome coronavirus. Journal of virology, 79(3), 1635-1644.
ELISA
Figure 2 Binding of human IgGs to N protein analyzed by ELISA.
Titration of IgGs CR3009, CR3018, and negative control IgG to the N protein.
van den Brink, E. N., ter Meulen, J., Cox, F., Jongeneelen, M. A., Thijsse, A., Throsby, M., ... & Martina, B. E. (2005). Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acutory syndrome coronavirus. Journal of virology, 79(3), 1635-1644.
IF
Figure 3 Binding of the IgGs to SARS-CoV-infected Vero cells.
Immunofluorescent staining with IgG CR3018.
van den Brink, E. N., ter Meulen, J., Cox, F., Jongeneelen, M. A., Thijsse, A., Throsby, M., ... & Martina, B. E. (2005). Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acutory syndrome coronavirus. Journal of virology, 79(3), 1635-1644.
EM
Figure 4 Visualization of N protein by ultrathin-section immuno-EM.
Gold immunolabeling of N protein in SARS-CoV-infected Vero cells with CR3018, followed by incubation with 5-nm-colloidal-gold-conjugated secondary antibody.
van den Brink, E. N., ter Meulen, J., Cox, F., Jongeneelen, M. A., Thijsse, A., Throsby, M., ... & Martina, B. E. (2005). Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acutory syndrome coronavirus. Journal of virology, 79(3), 1635-1644.
Inhib
Figure 5 Inhibition of the interaction of S565 with Vero cells by human IgG measured by fluorescence-activated cell sorting.
Vero cells were incubated with S-protein-derived fragment S565 in the absence (thin line) or presence (solid line) of IgG CR3018. The dotted line represents the negative control (irrelevant myc-tagged protein).
van den Brink, E. N., ter Meulen, J., Cox, F., Jongeneelen, M. A., Thijsse, A., Throsby, M., ... & Martina, B. E. (2005). Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acutory syndrome coronavirus. Journal of virology, 79(3), 1635-1644.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- SARS-CoV
- Species Reactivity
- SARS-CoV
- Clone
- 03-018
- Applications
- ELISA, IF, EM, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The SARS-CoV antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunofluorescence, Electron Microscopy, Inhibition.
Target
- Alternative Names
- Severe acute respiratory syndrome-related coronavirus; SARS-CoV
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-885 | Recombinant Anti-SARS-CoV Antibody | ELISA, WB, FC, FuncS | IgG |
| HPAB-0297CQ | Recombinant Human Anti-SARS-CoV Antibody (HuMAb 03-014) | ELISA, FC, Neut | Human IgG1 |
| HPAB-0102LY | Recombinant Anti-SARS-CoV Antibody (S227.14) | ELISA, RIA, Inhib | |
| HPAB-2048-FY | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-014) | ELISA, FC | Human IgG |
| HPAB-2049-FY | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-022) | ELISA, FC | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-885-F(E) | Recombinant Human Anti-SARS-CoV Antibody Fab Fragment | IP, RIA, FuncS | Fab |
| HPAB-0102LY-F(E) | Anti-SARS-CoV Antibody Fab Fragment (S227.14) | ELISA, RIA | Fab |
| HPAB-0103LY-F(E) | Anti-SARS-CoV Antibody Fab Fragment (S230.15) | ELISA, RIA | Fab |
| HPAB-0104LY-F(E) | Anti-SARS-CoV Antibody Fab Fragment (S109.8) | ELISA, RIA | Fab |
| HPAB-1909-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-001); Fab Fragment | ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-649LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-649LC-S(P)) | ELISA | Mouse scFv |
| MRO-650LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-650LC-S(P)) | ELISA | Mouse scFv |
| MRO-651LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-651LC-S(P)) | ELISA | Mouse scFv |
| MRO-652LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-652LC-S(P)) | ELISA | Mouse scFv |
| MRO-649LC-F(E) | Mouse Anti-SARS-CoV Recombinant Antibody; Fab Fragment (MRO-649LC-F(E)) | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0102LY-S(P) | Anti-SARS-CoV Antibody scFv Fragment (S227.14) | ELISA, RIA | scFv |
| HPAB-0103LY-S(P) | Anti-SARS-CoV Antibody scFv Fragment (S230.15) | ELISA, RIA | scFv |
| HPAB-0104LY-S(P) | Anti-SARS-CoV Antibody scFv Fragment (S109.8) | ELISA, RIA | scFv |
| HPAB-2048-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-014); scFv Fragment | Neut, ELISA, FC | Human scFv |
| HPAB-2049-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-022); scFv Fragment | Neut, ELISA, FC | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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