Human Anti-SELP Recombinant Antibody (clone CY1748) (CAT#: HPAB-0041-YJ)
This product is a recombinant humanized antibody that recognizes human P-selectin. Mab CY1748 reacts with the epitope aa 448-467 of human P-selectin. It inhibits adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo and functions in the treatment of inflammation and other pathological conditions.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2145/5903_A_9_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2145/5903_A_9_3.jpg
Figure 2 RNA cell line category: Group enriched (EFO-21, HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
Figure 2 RNA cell line category: Group enriched (EFO-21, HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
Specifications
- Immunogen
- Cells bearing P-selectin (e.g., thrombin-activated platelets), isolated P-selectin molecules or fragments thereof, such as extracellular domains
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG1, κ
- Specificity
- Human SELP
- Species Reactivity
- Human
- Clone
- CY1748
- Applications
- RIA, ELISA, Block
- Related Disease
- Diseases of the immune system, Acute lung injury, Ischemic reperfusion
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Selectin P; Platelet Activation Dependent Granule-External Membrane Protein; Selectin P (Granule Membrane Protein 140kDa, Antigen CD62); Leukocyte-Endothelial Cell Adhesion Molecule 3; CD62 Antigen-Like Family Member P; Granule Membrane Protein 140kDa; Granule Membrane Protein 140; GMP-140; LECAM3; PADGEM; GRMP; Selectin P (Granule Membrane Protein 140kD, Antigen CD62); CY-1748; CY1748
- Gene ID
- 6403
- UniProt ID
- P16109
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone CY1748"
See other products for "SELP"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-985 | Recombinant Mouse Anti-Human SELP Antibody F(ab')2 Fragment, clone G1/G1-4 | FC, FX | F(ab')2 |
| HPAB-0257-YC-F(E) | Mouse Anti-SELP Recombinant Antibody (clone 5C7.29); Fab Fragment | FC, Block | Mouse Fab |
| HPAB-0258-YC-F(E) | Human Anti-SELP Recombinant Antibody (clone hu5C7.29); Fab Fragment | FC, Block | Humanized Fab |
| HPAB-0259-YC-F(E) | Mouse Anti-SELP Recombinant Antibody (clone PB1.3); Fab Fragment | ELISA, Block | Mouse Fab |
| HPAB-0260-YC-F(E) | Human Anti-SELP Recombinant Antibody (clone huPB1.3); Fab Fragment | ELISA | Humanized Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-246 | Anti-Human selectin P Recombinant Antibody (Inclacumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - kappa |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-263CT | Mouse Anti-SELP Recombinant Antibody (TAB-263CT) | Inhib, FC | Mouse IgG |
| TAB-263CT-S(P) | Mouse Anti-SELP Recombinant Antibody; scFv Fragment (TAB-263CT-S(P)) | WB, ELISA | Mouse scFv |
| TAB-263CT-F(E) | Mouse Anti-SELP Recombinant Antibody; Fab Fragment (TAB-263CT-F(E)) | WB, ELISA | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-264CT | Humanized Anti-SELP Recombinant Antibody (TAB-264CT) | WB, ELISA | Humanized antibody |
| TAB-264CT-S(P) | Humanized Anti-SELP Recombinant Antibody; scFv Fragment (TAB-264CT-S(P)) | WB, ELISA | Humanized scFv |
| TAB-264CT-F(E) | Humanized Anti-SELP Recombinant Antibody; Fab Fragment (TAB-264CT-F(E)) | WB, ELISA | Humanized Fab |
| TAB-015ML | Anti-Human SELP Recombinant Antibody (Crizanlizumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1933CQ | Recombinant Mouse Anti-SELP Antibody (AK4) | WB, IP, FuncS, ICC, FC, BL | IgG1 |
| NEUT-1934CQ | Recombinant Mouse Anti-Selp Antibody (RMP-1) | FC, IF, IHC, ELISA, WB, IP, BL | IgG2a, κ |
| NEUT-1936CQ | Recombinant Mouse Anti-SELP Antibody (VMC207) | BL, IHC | IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1935CQ | Recombinant Mouse Anti-Selp Antibody (Psel.KO2.12) | FC, FuncS, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3203 | Hi-Affi™ Recombinant Rabbit Anti-SELP Monoclonal Antibody (DS3203AB) | WB, IHC-P | IgG |
| MOR-4550 | Hi-Affi™ Recombinant Rabbit Anti-SELP Monoclonal Antibody (TH60DS) | WB, IF, ICC, FC, ELISA | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0257-YC | Mouse Anti-SELP Recombinant Antibody (clone 5C7.29) | FC, Block | Mouse IgG |
| HPAB-0258-YC | Human Anti-SELP Recombinant Antibody (clone hu5C7.29) | FC, Block | Humanized IgG |
| HPAB-0259-YC | Mouse Anti-SELP Recombinant Antibody (clone PB1.3) | ELISA, Block | Mouse IgG |
| HPAB-0260-YC | Human Anti-SELP Recombinant Antibody (clone huPB1.3) | ELISA | Humanized IgG, κ |
| MRO-0312-CN | Recombinant Rabbit Anti-SELP Monoclonal Antibody (JM10-95) | WB, IHC | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-015ML | Afuco™ Anti-SELP ADCC Recombinant Antibody (Crizanlizumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-246 | Afuco™ Anti-SELP ADCC Recombinant Antibody (Inclacumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP431-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 001); scFv Fragment | ELISA | Human scFv |
| HPAB-AP432-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 002); scFv Fragment | ELISA | Human scFv |
| HPAB-AP433-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 002 IgG4v1); scFv Fragment | ELISA | Human scFv |
| HPAB-AP434-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 003); scFv Fragment | ELISA | Human scFv |
| HPAB-AP435-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 004I); scFv Fragment | ELISA | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0041-YJ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.