Rabbit Anti-SELPLG Recombinant Antibody (clone R03-8N8) (CAT#: VS3-XY3498)
This is a recombinant rabbit antibody that specifically recognizes human SELPLG (Selectin P ligand), which is critical for the initial leukocyte capture. The antibody also has cross-reactivity against mouse or rat SELPLG. It has been reported for use in Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation, Immunocytochemistry or Immunofluorescence.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11256/1847_F9_37_cr5abb5d8e30c09_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11256/1847_F9_37_cr5abb5d8e30c09_selected.jpg
Figure 2 High expression in spleen.
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2431/6181_B_8_4_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2431/6181_B_8_4_val_selected.jpg
Figure 3 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_5.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69062/170043_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, JURKAT, Karpas-707, RPMI-8226, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110876-SELPLG
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110876-SELPLG
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human SELPLG
- Species Reactivity
- Human
- Clone
- R03-8N8
- Applications
- WB, IHC-P, ICC, IF, IP
- Related Disease
- Hand, Foot And Mouth Disease; Human Granulocytic Anaplasmosis
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
IP: 1/20
Target
- Alternative Names
- CLA; CD162; PSGL1; PSGL-1
- Gene ID
- 6404
- UniProt ID
- Q14242
- Long Name
- Selectin P ligand
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylation at Thr57, Asn65, Asn111, Ser287, Ser289, Ser290, Thr292, and Asn302 (NX_Q14242 [NX_Q14242-1])
Ubiquitination at Lys386 (NX_Q14242 [NX_Q14242-1])
Modification sites at PhosphoSitePlus (Q14242)
Glycosylation from GlyConnect SELPL_HUMAN (520)
Glycosylation from GlyGen (Q14242) 12 sites, 10 O-linked glycans (8 sites)
- Protein Refseq
- NP_002997.2
- Function
- A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation.
Critical for the initial leukocyte capture. SELPL_HUMAN,Q14242
(Microbial infection) Acts as a receptor for enterovirus 71.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "SELPLG"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-555CL | Human Anti-SELPLG Recombinant Antibody (TAB-555CL) | ELISA | Human IgG |
Mouse Antibody
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-265CT-S(P) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody scFv Fragment | WB, ELISA | Human antibody |
| TAB-269CT-S(P) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody scFv Fragment (PSG3) | ELISA, FC | Human antibody |
| TAB-270CT-S(P) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody scFv Fragment (PSG5) | ELISA, FC | Human antibody |
| TAB-271CT-S(P) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody scFv Fragment (PSG6) | ELISA, FC | Human antibody |
| TAB-265CT-F(E) | Anti-Human P-selectin glycoprotein ligand 1 (PSGL-1) Recombinant Antibody Fab Fragment | WB, ELISA | Human antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1937CQ | Recombinant Mouse Anti-SELPLG Antibody (KPL-1) | BL, WB, IP, IHC-P, IHC-Fr, FC | IgG1, κ |
| NEUT-1938CQ | Recombinant Mouse Anti-SELPLG Antibody (3E2.25.5) | BL, FC, IHC, IHC-Fr, IHC-P, WB | IgG1 |
| NEUT-1939CQ | Recombinant Rat Anti-Selplg Antibody (4RA10) | BL, IHC | IgG1 |
| NEUT-1940CQ | Recombinant Mouse Anti-SELPLG Antibody (CHO131) | BL, CyTOF, FC | IgM |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3204 | Hi-Affi™ Recombinant Rabbit Anti-SELPLG Monoclonal Antibody (DS3204AB) | WB, IP, IHC | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0597-CN-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0597-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0101-LS-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0101-LS-S(P)) | ELISA | Mouse scFv |
| HPAB-0102-LS-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0102-LS-S(P)) | ELISA | Mouse scFv |
| HPAB-0103-LS-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0103-LS-S(P)) | ELISA | Mouse scFv |
| HPAB-0106-LS-S(P) | Mouse Anti-SELPLG Recombinant Antibody; scFv Fragment (HPAB-0106-LS-S(P)) | Inhib | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0101-LS-F(E) | Mouse Anti-SELPLG Recombinant Antibody; Fab Fragment (HPAB-0101-LS-F(E)) | ELISA | Mouse Fab |
| HPAB-0102-LS-F(E) | Mouse Anti-SELPLG Recombinant Antibody; Fab Fragment (HPAB-0102-LS-F(E)) | ELISA | Mouse Fab |
| HPAB-0103-LS-F(E) | Mouse Anti-SELPLG Recombinant Antibody; Fab Fragment (HPAB-0103-LS-F(E)) | ELISA | Mouse Fab |
| HPAB-0106-LS-F(E) | Mouse Anti-SELPLG Recombinant Antibody; Fab Fragment (HPAB-0106-LS-F(E)) | Inhib | Mouse Fab |
| HPAB-0911-FY-S(P) | Mouse Anti-SELPLG Recombinant Antibody (clone M-DC8); Fab Fragment | FC | Mouse Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-058CQ | Recombinant Mouse Anti-SELPLG Antibody (PL1) | FC, Block, WB | Mouse IgG1 |
| HPAB-0911-FY | Mouse Anti-SELPLG Recombinant Antibody (clone M-DC8) | FC | Mouse IgM |
| MOB-259YJL | Rabbit Anti-SELPLG Recombinant Antibody (clone CBS244), PE | FC | Rabbit IgG |
| ZG-0025U | Rabbit Anti-SELPLG Recombinant Antibody (clone 3G11) | ELISA, IHC | Rabbit IgG |
| VS3-FY249 | Recombinant Mouse Anti-SELPLG Antibody (clone 3D5H1) | ELISA, IHC, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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