This product is a recombinant rabbit antibody that recognizes SIRPB1. The antibody was purified by affinity chromatography. It can be used in SPR, ELISA, FC.
Figure 1 Analysis of OX130 MAb binding to SIRP proteins by SPR.
Overlay of specific binding traces showing OX130 bound well to both alleles of SIRPβ1 but only one allele of SIRPα(1). There is some weak transient binding to SIRPγ. Immobilization levels of SIRP proteins shown are SIRPα(1) 862 response units (RU); SIRPα(10) 956 RU; SIRPβ1(1) 953 RU; SIRPβ1(2) 999 RU; and SIRPγ 1129 RU. Bar indicates where OX130 was passed over flow cell. Background signal determined on a control CD4 flow cell was subtracted from all traces. SPR, surface plasmon resonance.
Hatherley, D., Aknin, M. L., & Barclay, A. N. (2016). OX130 Monoclonal Antibody Recognizes Human SIRPβ1 but Cross-Reacts on SIRPα from One Allele. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 35(1), 57-59.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1382CT | Recombinant Mouse anti-Human SIRPB1 Monoclonal antibody (EML750) | FC, IP, WB |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3266 | Hi-Affi™ Recombinant Rabbit Anti-SIRPB1 Monoclonal Antibody (DS3266AB) | ELISA, WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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