Rabbit Anti-SIRPB1 Recombinant Antibody (clone OX130) (CAT#: FAMAB-1256CQ)

This product is a recombinant rabbit antibody that recognizes SIRPB1. The antibody was purified by affinity chromatography. It can be used in SPR, ELISA, FC.


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SPR

Figure 1 Analysis of OX130 MAb binding to SIRP proteins by SPR.

Figure 1 Analysis of OX130 MAb binding to SIRP proteins by SPR.

Overlay of specific binding traces showing OX130 bound well to both alleles of SIRPβ1 but only one allele of SIRPα(1). There is some weak transient binding to SIRPγ. Immobilization levels of SIRP proteins shown are SIRPα(1) 862 response units (RU); SIRPα(10) 956 RU; SIRPβ1(1) 953 RU; SIRPβ1(2) 999 RU; and SIRPγ 1129 RU. Bar indicates where OX130 was passed over flow cell. Background signal determined on a control CD4 flow cell was subtracted from all traces. SPR, surface plasmon resonance.

Hatherley, D., Aknin, M. L., & Barclay, A. N. (2016). OX130 Monoclonal Antibody Recognizes Human SIRPβ1 but Cross-Reacts on SIRPα from One Allele. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 35(1), 57-59.


Specifications

  • Immunogen
  • Recombinant SIRPB1
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Species Reactivity
  • Human
  • Clone
  • OX130
  • Applications
  • SPR, ELISA, FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Signal Regulatory Protein Beta 1; CD172 Antigen-Like Family Member B; SIRP-BETA-1; Signal-Regulatory Protein Beta 1; Signal-Regulatory Protein Beta-1; SIRP-Beta-1 Isoform 3; CD172b Antigen; CD172b

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Recombinant Antibody

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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