Mouse Anti-SLC3A2 Recombinant Antibody (clone C17) (CAT#: FAMAB-0169JF)
Recombinant monoclonal antibody specially binds to human solute carrier family 3 member 2 (SLC3A2/CD98). This mouse anti-CD98 antibody (C17) can be useful in the development of vaccines against native CD98 on tumor cells.
Specific Inquiry
IF
Figure 1 Immunofluoresence stained with 3G9 mAb showing the expression of 3G9Ag in gastric cancer cell lines.
Transwell chamber assay without or with Matrigel showed the migration and invasion of gastric cells.
Wang, S., Han, H., Hu, Y., Yang, W., Lv, Y., Wang, L., ... & Ji, J. (2017). SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer. Oncotarget, 8(51), 88586.
WB
Figure 2 Western blot for SLC3A2 and GAPDH in GFP and SLC3A2 overexpressing NCI-N87 cells.
Overexpression of SLC3A2 promoted the migration and invasion in NCI-N87 cells.
Wang, S., Han, H., Hu, Y., Yang, W., Lv, Y., Wang, L., ... & Ji, J. (2017). SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer. Oncotarget, 8(51), 88586.
FC
Figure 3 Characterization of CD98hc- conditional allele.
Conditional allele strategy. Representation of WT CD98hc locus and the targeted allele after CRE recombination.
Wang, S., Han, H., Hu, Y., Yang, W., Lv, Y., Wang, L., ... & Ji, J. (2017). SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer. Oncotarget, 8(51), 88586.
ELISA
Figure 4 CD98hc mediates adhesion-induced RhoA activation and matrix contraction to enable Fn matrix assembly.
Activation of RhoA by LPA in WT and CD98hc-null MEFs.
Wang, S., Han, H., Hu, Y., Yang, W., Lv, Y., Wang, L., ... & Ji, J. (2017). SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer. Oncotarget, 8(51), 88586.
Specifications
- Immunogen
- Mimotope–KLH conjugates
- Host Species
- Mouse
- Derivation
- Mouse phage display Fab library
- Type
- Mouse IgG
- Specificity
- Human SLC3A2
- Species Reactivity
- Human
- Clone
- C17
- Applications
- WB, ELISA, IF, FC
- Related Disease
- Tumors
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The SLC3A2 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunofluorescence, Flow Cytometry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1096z | Mouse Anti-SLC3A2 Recombinant Antibody (clone 18C10) | FC, IF, FuncS | Mouse IgG1, κ |
| MOB-0528CT | Recombinant Mouse anti-Human SLC3A2 Monoclonal antibody (55E8) | FC, ICC/IF, IHC-Fr, IP | |
| HPAB-0123-CN | Mouse Anti-SLC3A2 Recombinant Antibody (HPAB-0123-CN) | ELISA, FC, IHC | Mouse IgG |
| HPAB-0124-CN | Mouse Anti-SLC3A2 Recombinant Antibody (HPAB-0124-CN) | ELISA, FC, IHC | Mouse IgG |
| HPAB-0125-CN | Human Anti-SLC3A2 Recombinant Antibody (HPAB-0125-CN) | ELISA, FC, IHC | Humanized IgG |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1974CQ | Recombinant Human Anti-SLC3A2 Antibody (HBJ127) | BL, Activation, ELISA, IF | IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3303 | Hi-Affi™ Recombinant Rabbit Anti-SLC3A2 Monoclonal Antibody (DS3303AB) | IHC-P, IP, WB | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0123-CN-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody; scFv Fragment (HPAB-0123-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
| FAMAB-0167JF-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody (clone A18); scFv Fragment | IF, ELISA, FuncS | Mouse scFv |
| FAMAB-0168JF-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody (clone B3); scFv Fragment | IF, ELISA, FuncS | Mouse scFv |
| FAMAB-0169JF-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody (clone C17); scFv Fragment | IF, ELISA, FuncS | Mouse scFv |
| PABJ-0174-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody (clone MEM-108); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0123-CN-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody; Fab Fragment (HPAB-0123-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0124-CN-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody; Fab Fragment (HPAB-0124-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0125-CN-F(E) | Human Anti-SLC3A2 Recombinant Antibody; Fab Fragment (HPAB-0125-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
| FAMAB-0167JF-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody (clone A18); Fab Fragment | IF, ELISA, FuncS | Mouse Fab |
| PABJ-0174-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody (clone MEM-108); Fab Fragment | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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