Rabbit Anti-SPTAN1 Recombinant Antibody (clone R01-9G3) (CAT#: VS3-XY3513)
The rabbit recombinant antibody specifically recognizes SPTAN1 (Spectrin alpha, non-erythrocytic 1). This antibody specifically reacts with human, mouse and rat SPTAN1. It has been tested using Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation. The recommended dilutions of Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation is 1/500-1/1000, 1/50-1/100 and 1/20.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to microtubules & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7927/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to microtubules & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7927/if_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Neuropil
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4581/13221_B_7_5.jpg
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Neuropil
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4581/13221_B_7_5.jpg
Figure 3 Colon
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4581/13221_A_7_3.jpg
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4581/13221_A_7_3.jpg
Figure 4 Pancreas
(Exocrine glandular cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4581/13221_A_1_3.jpg
(Exocrine glandular cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4581/13221_A_1_3.jpg
Figure 5 Kidney
(Cells in glomeruli
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4581/13221_A_8_5.jpg
(Cells in glomeruli
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4581/13221_A_8_5.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197694-SPTAN1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197694-SPTAN1
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197694-SPTAN1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197694-SPTAN1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat SPTAN1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R01-9G3
- Applications
- WB, IHC-P, IP
- Related Disease
- Developmental And Epileptic Encephalopathy 5; Neuronopathy, Distal Hereditary Motor, Autosomal Dominant 11
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IP: 1/20
Target
- Alternative Names
- DEE5; NEAS; DEVEP; EIEE5; HMN11; SPG91; SPTA2; HMND11
- Gene ID
- 6709
- UniProt ID
- Q13813
- Long Name
- Spectrin alpha, non-erythrocytic 1
- Cellular Localization
- Cytoplasm, cytoskeleton, cell cortex
- Post Translation Modifications
- Phosphorylation of Tyr-1176 decreases sensitivity to cleavage by calpain in vitro. (Q13813-SPTN1_HUMAN)
Ubiquitination at Lys1519 and Lys2426 (NX_Q13813 [NX_Q13813-1])
Modification sites at PhosphoSitePlus (Q13813)
Glycosylation from GlyGen (Q13813) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_016870549.1
- Function
- Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "SPTAN1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1304z | Mouse Anti-SPTAN1 Recombinant Antibody (clone 32D6) | WB, IP, IF, IHC, ELISA | Mouse IgG1, κ |
| MOB-0596MZ | Recombinant Mouse Anti-Human SPTAN1 Antibody (clone E9C8) | ELISA, IHC-Fr, IHC-P, IP, WB | Mouse antibody |
| MRO-0066-CN | Recombinant Rabbit Anti-SPTAN1 Monoclonal Antibody (JU32-09) | WB, IHC | Rabbit IgG |
| VS3-FY1385 | Recombinant Rabbit Anti-SPTAN1 Antibody (clone R08-7C6) | WB, ICC, IF | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3400 | Hi-Affi™ Recombinant Rabbit Anti-SPTAN1 Monoclonal Antibody (DS3400AB) | IP, WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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