Rabbit Anti-THBD Recombinant Antibody (clone R08-4C6) (CAT#: VS3-FY1601)

The R08-4C6 recombinant monoclonal antibody has been meticulously designed to target human THBD. It is suitable for use in a variety of assays, including WB, ICC/IF, IP. The specificity of the thrombomodulin antibody was confirmed by western blot analysis of thrombomodulin in Jurkat lysates.


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WB

Figure 1 Anti-THBD Antibody (VS3-FY1601) in WB.

Figure 1 Anti-THBD Antibody (VS3-FY1601) in WB.

The Thrombomodulin expression in Jurkat lysates were detected using the anti-Thrombomodulin (THBD) by western blot assay.


Specifications

  • Immunogen
  • Synthetic peptide of human thrombomodulin
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human THBD
  • Species Reactivity
  • Human
  • Clone
  • R08-4C6
  • Applications
  • Western Blot, Immunofluorescence, Immunoprecipitation
  • MW
  • The calculated weight of the target protein is approximately 60 kDa, while the observed molecular weight stands at 95 kDa.
  • Related Disease
  • Thromboembolic disease

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunofluorescence: 1/50-1/200
    Immunoprecipitation: 1/20

Target

  • Alternative Names
  • Thrombomodulin; CD141 Antigen; Fetomodulin; THRM; TM; THPH12; AHUS6; BDCA3; CD141
  • Cellular Localization
  • Membrane
  • Post Translation Modifications
  • N-glycosylated., The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
  • Function
  • Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Recommended Products

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Thbd"

Single-domain Antibody

CAT Product Name Application Type
NAB-1329-VHH Recombinant Anti-Mouse Thbd VHH Single Domain Antibody IHC, ICC, FC, FA, FUNC Llama VHH

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3559 Rabbit Anti-THBD Recombinant Antibody (clone DS3559AB) WB Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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