Rat Anti-Tlr4 Recombinant Antibody (clone Sa 15-21) (CAT#: HPAB-0318CQ)
This product is a recombinant Rat antibody that can bind to mouse TLR4 with high affinity.
Specific Inquiry
FC
Figure 1 LPS-dependent oligomerization of TLR4.
(c) Ba/F3 cells expressing muTLR4F/muTLR4G/muMD-2F/muCD14 were subjected to LPS stimulation (1 μg/mL) for the indicated periods of time, and staining with a mAb to muTLR4-MD-2, Sa 15-21. Open histograms depict staining with the second reagent, streptavidin-PE, alone.
Saitoh, S. I., Akashi, S., Yamada, T., Tanimura, N., Kobayashi, M., Konno, K., ... & Kusumoto, Y. (2004). Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll‐like receptor 4 (TLR4)‐MD‐2 and ligand‐induced TLR4 oligomerization. International immunology, 16(7), 961-969.
Specifications
- Immunogen
- LPS-stimulated TLR4/MD-2/CD14 cotransfected NKR cells
- Host Species
- Rat
- Type
- Rat IgG2a, κ
- Specificity
- Mouse Tlr4
- Species Reactivity
- Mouse
- Clone
- Sa 15-21
- Applications
- FC, IP, Apop, IHC, WB, Inhib, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry, Immunohistochemistry, Western Blot, Inhibition and Functional Assay. Please see the Published Data for further information.
Target
- Alternative Names
- Toll Like Receptor 4; Toll-Like Receptor 4; HToll; Homolog Of Drosophila Toll; CD284 Antigen; ARMD10; CD284; TLR-4; TOLL;
- Gene ID
- 21898
- UniProt ID
- Q9JLF7
Related Resources
NLR Signaling Pathway
TLR Signaling Pathway
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-613CL | Human Anti-TLR4 Recombinant Antibody (TAB-613CL) | FuncS | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-722 | Human Anti-TLR4 Recombinant Antibody; Fab Fragment (PFBL-722) | Neut | Human Fab |
| HPAB-AP199-YC-F(E) | Human Anti-TLR4 Recombinant Antibody; Fab Fragment (HPAB-AP199-YC-F(E)) | ELISA, FC, Inhib | Human Fab |
| HPAB-AP200-YC-F(E) | Human Anti-TLR4 Recombinant Antibody; Fab Fragment (HPAB-AP200-YC-F(E)) | ELISA, FC, Inhib | Human Fab |
| HPAB-AP201-YC-F(E) | Human Anti-TLR4 Recombinant Antibody; Fab Fragment (HPAB-AP201-YC-F(E)) | ELISA, FC, Inhib | Human Fab |
| HPAB-AP202-YC-F(E) | Human Anti-TLR4 Recombinant Antibody; Fab Fragment (HPAB-AP202-YC-F(E)) | ELISA, FC | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-181 | Human Anti-TLR4 Recombinant Antibody (PABX-181) | WB, ELISA, FuncS | Human IgG |
| PABX-181-F (E) | Human Anti-TLR4 Recombinant Antibody; Fab Fragment (PABX-181-F (E)) | WB, ELISA, FuncS | Human Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-181-S (P) | Human Anti-TLR4 Recombinant Antibody; scFv Fragment (PABX-181-S (P)) | WB, ELISA, FuncS | Human scFv |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2036CQ | Recombinant Rat Anti-Tlr4 Antibody (MTS510) | FC, IHC, ICFC, IF, IP, BL | IgG2a, κ |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2037CQ | Mouse Anti-TLR4 Recombinant Antibody (clone 3C3) | Neut, FC | Mouse IgG1 |
| NEUT-2038CQ | Mouse Anti-TLR4 Recombinant Antibody (clone CBL961) | FC, ICC, IF, IP, Neut | Mouse IgG2a, κ |
| NEUT-2039CQ | Mouse Anti-TLR4 Recombinant Antibody (clone HTA125) | ICC, IP, FC, Neut | Mouse IgG2a |
| NEUT-2040CQ | Mouse Anti-TLR4 Recombinant Antibody (clone W7C11) | Neut | Mouse IgG1 |
| NEUT-2041CQ | Mouse Anti-TLR4 Recombinant Antibody (clone 7E3) | Neut, FC | Mouse IgG1 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2226-CN | Rabbit Anti-TLR4 Polyclonal Antibody (MRO-2226-CN) | IF, IHC, FC, WB | Rabbit IgG |
| HPAB-AP199-YC | Human Anti-TLR4 Recombinant Antibody (HPAB-AP199-YC) | FC, ELISA, Inhib | Human IgG |
| HPAB-AP200-YC | Human Anti-TLR4 Recombinant Antibody (HPAB-AP200-YC) | FC, ELISA, Inhib | Human IgG |
| HPAB-AP201-YC | Human Anti-TLR4 Recombinant Antibody (HPAB-AP201-YC) | ELISA, FC, Inhib | Human IgG |
| HPAB-AP202-YC | Human Anti-TLR4 Recombinant Antibody (HPAB-AP202-YC) | ELISA, FC | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP199-YC-S(P) | Human Anti-TLR4 Recombinant Antibody; scFv Fragment (HPAB-AP199-YC-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-AP200-YC-S(P) | Human Anti-TLR4 Recombinant Antibody; scFv Fragment (HPAB-AP200-YC-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-AP201-YC-S(P) | Human Anti-TLR4 Recombinant Antibody; scFv Fragment (HPAB-AP201-YC-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-AP202-YC-S(P) | Human Anti-TLR4 Recombinant Antibody; scFv Fragment (HPAB-AP202-YC-S(P)) | ELISA, FC | Human scFv |
| HPAB-0678YY-S(P) | Human Anti-TLR4 Recombinant Antibody (clone CBT111YJ); scFv Fragment | ELISA, Inhib | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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