Human Anti-VACV B5R Recombinant Antibody (clone 303) (CAT#: FAMAB-0018JF)
Recombinant monoclonal antibody specially binds to VACV antigens B5R. This anti-VACV B5R monoclonal antibody 303 can be wildey used as an effective postexposure prophylaxis or treatment of disease caused by orthopoxviruses.
Specific Inquiry
ELISA
Figure 1 B5R-specific ELISA.
The mean O.D. values and standard deviations for the nine mice in each group are shown.
Hooper, J. W., Custer, D. M., & Thompson, E. (2003). Four-gene-combination DNA vaccine protects mice against a lethal vaccinia virus challenge and elicits appropriate antibody responses in nonhuman primates. Virology, 306(1), 181-195.
WB
Figure 2 Antibodies elicited by DNA vaccination with vaccinia-based plasmids react with monkeypox virus orthologous proteins.
Data are representative of at least 3 independent experiments.
Hooper, J. W., Custer, D. M., & Thompson, E. (2003). Four-gene-combination DNA vaccine protects mice against a lethal vaccinia virus challenge and elicits appropriate antibody responses in nonhuman primates. Virology, 306(1), 181-195.
IHC
Figure 3 Macroscopic and histological lesions observed in naive monkeys infected with MPXV.
Macroscopic and histological lesions in the skin, lungs, and pancreas in the IN group.
Saijo, M., Ami, Y., Suzaki, Y., Nagata, N., Iwata, N., Hasegawa, H., ... & Kurata, T. (2006). LC16m8, a highly attenuated vaccinia virus vaccine lacking expression of the membrane protein B5R, protects monkeys from monkeypox. Journal of virology, 80(11), 5179-5188.
Specifications
- Immunogen
- VACV particles
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Vaccinia virus B5R
- Species Reactivity
- Human
- Clone
- 303
- Applications
- WB, ELISA, IHC
- Related Disease
- Orthopoxvirus infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The VACV B5R antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 303"
See other products for "VACV B5R"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1032 | Recombinant Anti-VACV B5R Antibody | ELISA, WB, FuncS | IgG |
| MHH-1032 | Recombinant Human Anti-VACV B5R Antibody | FC, Neut, Funcs | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1032-F(E) | Recombinant Anti-VACV B5R Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| MHH-1032-F(E) | Recombinant Human Anti-VACV B5R Antibody Fab Fragment | FC, IP, FuncS | Fab |
| FAMAB-0018JF-F(E) | Human Anti-VACV B5R Recombinant Antibody (clone 303); Fab Fragment | FLISA, WB, ELISA, FACS, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1032-S(P) | Recombinant Anti-VACV B5R Antibody scFv Fragment | WB, IHC, FuncS | scFv |
| MHH-1032-S(P) | Recombinant Human Anti-VACV B5R Antibody scFv Fragment | FC, Neut, Biosensors, FuncS | scFv |
| FAMAB-0018JF-S(P) | Human Anti-VACV B5R Recombinant Antibody (clone 303); scFv Fragment | FLISA, WB, ELISA, FACS, FuncS | Human scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1183LC | Anti-VACV B5R Recombinant Antibody (hB5RmAb) | ELISA, WB | Humanized antibody |
| MRO-1183LC-S(P) | Anti-VACV B5R Recombinant Antibody scFv Fragment (hB5RmAb) | ELISA, WB | Humanized antibody |
| MRO-1183LC-F(E) | Anti-VACV B5R Recombinant Antibody Fab Fragment (hB5RmAb) | ELISA, WB | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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