Human Anti-VEGF Recombinant Antibody (clone E9) (CAT#: HPAB-J0265-YC)

Provided is a vascular endothelial growth factor (VEGF) -specific human antibody, and more particularly to a human antibody including a complementarity determining region (CDR) and a framework region (FR) derived from a human antibody specifically bound to VEGF. E9 monoclonal antibody showing binding capacities similar to that of Avastin™ all exhibited strong affinities for mouse VEGF similar to those for human VEGF, leading to a cross reaction. The VEGF- specific human antibody may be used in diagnosis of diseases caused by the VEGF-overexpression, classification of the diseases, visualization, treatment, and prognostic evaluation.


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ELISA

Figure 1 illustrating results of the measurement of cross-reactivity of human VEGF monoclonal antibodies with hVEGF and mVEGF.

Figure 1 illustrating results of the measurement of cross-reactivity of human VEGF monoclonal antibodies with hVEGF and mVEGF.

ELISA

Figure 2 illustrating results comparing binding specificities of human VEGF monoclonal antibodies.

Figure 2 illustrating results comparing binding specificities of human VEGF monoclonal antibodies.


Specifications

  • Host Species
  • Human
  • Derivation
  • scFv antibody library
  • Type
  • Human IgG
  • Specificity
  • Human VEGF
  • Species Reactivity
  • Human, Mouse
  • Clone
  • E9
  • Applications
  • ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay.

Target

  • Alternative Names
  • Vascular endothelial growth factor; vascular permeability factor; VPF

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone E9"

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Recombinant Antibody

Fc Glycosylation

CAT Product Name Application Type
Gly-096LC Recombinant Anti-Human VEGF Antibody (Fc glycosylation) ELISA Humanized antibody
Gly-143LC Recombinant Anti-Human VEGF Antibody (Fc glycosylation) ELISA Humanized antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-179LC Recombinant Anti-Human VEGF Antibody (Non-glycosylated) ELISA Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4485 Rabbit Anti-VEGF Recombinant Antibody (clone SI581DS) ELISA Rabbit IgG

Single-domain Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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