Rabbit Anti-VWF Recombinant Antibody (clone R01-5D2) (CAT#: VS3-FY1936)
The rabbit recombinant monoclonal antibody is ideal for use in WB, IHC assays. This antibody shows high affinity in binding to human and rat VWF. The recommended application dilution human and ratio is: western blot (dilution 1/500-1/1000), immunohistochemistry (dilution 1/50-1/100).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Endothelial cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1694/4967_B_8_5.jpg
(Endothelial cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1694/4967_B_8_5.jpg
Figure 2 Colon
(Endothelial cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1694/4967_A_9_3.jpg
(Endothelial cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1694/4967_A_9_3.jpg
Figure 3 RNA cell line category: Cell line enriched (HUVEC TERT2)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000110799-VWF
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000110799-VWF
Figure 3 RNA cell line category: Cell line enriched (HUVEC TERT2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110799-VWF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110799-VWF
Specifications
- Immunogen
- Synthetic peptide of human von Willebrand factor
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat VWF
- Species Reactivity
- Human, Rat
- Clone
- R01-5D2
- Applications
- Western Blot, Immunohistochemistry-Paraffin
- MW
- The calculated weight of the target protein is approximately 309 kDa, while the observed molecular weight stands at 309 kDa.
- Related Disease
- Occlusive disease
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- Von Willebrand Factor; F8VWF; Coagulation Factor VIII VWF; VWD; VWF
- Gene ID
- 7450
- UniProt ID
- P04275
- Cellular Localization
- Extracellular matrix, Secreted
- Post Translation Modifications
- All cysteine residues are involved in intrachain or interchain disulfide bonds. (P04275-VWF_HUMAN)
N- and O-glycosylated. (P04275-VWF_HUMAN)
Glycosylation at Asn99, Asn156, Asn211, Asn368, Asn666, Asn857, Asn1147, Asn1231, Thr1248, Thr1255, Thr1256, Ser1263, Thr1468, Thr1477, Ser1486, Thr1487, Asn1515, Asn1574, Thr1679, Asn2223, Asn2290, Thr2298, Asn2357, Asn2400, Asn2546, Asn2585, and Asn2790 (NX_P04275 [NX_P04275-1])
Modification sites at PhosphoSitePlus (P04275)
Glycosylation from GlyConnect VWF_HUMAN (627)
Glycosylation from GlyGen (P04275) 30 sites, 112 N-linked glycans (12 sites), 10 O-linked glycans (8 sites)
- Protein Refseq
- XP_047285457.1; XP_054229108.1; NP_000543.3
- Function
- Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "VWF"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1149z | Mouse Anti-VWF Recombinant Antibody (clone 41C2) | WB, FC, IF, IHC, IP | Mouse IgG1, κ |
| FAMAB-0297YC | Human Anti-VWF Recombinant Antibody (clone h82D6A3) | Inhib | Humanized IgG4 |
| FAMAB-0298YC | Mouse Anti-VWF Recombinant Antibody (clone m-82D6A3) | Inhib | Mouse IgG |
| MRO-1590-CN | Rabbit Anti-VWF Recombinant Antibody (clone CBACN-582) | WB, IHC | Rabbit IgG |
| ZG-507C | Mouse Anti-VWF Recombinant Antibody (clone RU8) | ELISA, immunopurification of vWF | Mouse IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-132 | Mouse Anti-VWF Recombinant Antibody (clone 82D6A3); Fab Fragment | WB, IF, FuncS | Mouse Fab |
| PFBW-132 | Mouse Anti-VWF Recombinant Antibody (clone NMC-4); Fab Fragment | Block | Mouse Fab |
| FAMAB-0297-YC-F(E) | Human Anti-VWF Recombinant Antibody (clone h82D6A3); Fab Fragment | ELISA, WB | Humanized Fab |
| FAMAB-0298-YC-F(E) | Mouse Anti-VWF Recombinant Antibody (clone m-82D6A3); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-0343-WJ-F(E) | Mouse Anti-VWF Recombinant Antibody; Fab Fragment (HPAB-0343-WJ-F(E)) | ELISA, WB | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-132 | Mouse Anti-VWF Recombinant Antibody (clone 82D6A3); scFv Fragment | WB, IF, FuncS | Mouse scFv |
| PSBW-132 | Mouse Anti-VWF Recombinant Antibody (clone NMC-4); scFv Fragment | Block | Mouse scFv |
| PSBC-133 | Mouse Anti-VWF Recombinant Antibody (clone RU5); scFv Fragment | WB, IHC, IF, FuncS | Mouse scFv |
| FAMAB-0297-YC-S(P) | Human Anti-VWF Recombinant Antibody (clone h82D6A3); scFv Fragment | ELISA, WB | Humanized scFv |
| HPAB-0343-WJ-S(P) | Mouse Anti-VWF Recombinant Antibody; scFv Fragment (HPAB-0343-WJ-S(P)) | ELISA, WB | Mouse scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-362CQ | Anti-Human VWF Recombinant Antibody (AJvW-2) | ELISA, BL | |
| TAB-362CQ-S(P) | Anti-Human VWF Recombinant Antibody scFv Fragment (AJvW-2) | ELISA, BL | |
| TAB-363CQ-S(P) | Mouse Anti-VWF Recombinant Antibody; scFv Fragment (TAB-363CQ-S(P)) | ELISA, WB, Inhib | Mouse scFv |
| TAB-362CQ-F(E) | Anti-Human VWF Recombinant Antibody Fab Fragment (AJvW-2) | ELISA, BL | |
| TAB-363CQ-F(E) | Mouse Anti-VWF Recombinant Antibody; Fab Fragment (TAB-363CQ-F(E)) | ELISA, WB, Inhib | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-364CQ | Human Anti-VWF Recombinant Antibody (TAB-364CQ) | Inhib | Humanized antibody |
| TAB-364CQ-S(P) | Human Anti-VWF Recombinant Antibody; scFv Fragment (TAB-364CQ-S(P)) | Inhib | Humanized scFv |
| TAB-364CQ-F(E) | Human Anti-VWF Recombinant Antibody; Fab Fragment (TAB-364CQ-F(E)) | Inhib | Humanized Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-365CQ | Human Anti-VWF Recombinant Antibody (TAB-365CQ) | Inhib | Chimeric antibody (mouse/human) |
| TAB-365CQ-S(P) | Mouse Anti-VWF Recombinant Antibody; scFv Fragment (TAB-365CQ-S(P)) | Inhib | Mouse scFv |
| TAB-365CQ-F(E) | Human Anti-VWF Recombinant Antibody; Fab Fragment (TAB-365CQ-F(E)) | Inhib | Chimeric antibody (mouse/human) |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3860 | Rabbit Anti-VWF Recombinant Antibody (clone DS3860AB) | WB, ICC, IF | Rabbit IgG |
| MOR-0109-FY | Rabbit Anti-VWF Recombinant Antibody (clone AFY0080) | ICC, IHC-P, WB | Rabbit IgG |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1628-FY | Llama Anti-VWF Recombinant Single Domain Antibody (HPAB-1628-FY) | ELISA | Llama VHH |
| HPAB-1629-FY | Llama Anti-VWF Recombinant Single Domain Antibody (HPAB-1629-FY) | ELISA | Llama VHH |
| HPAB-1630-FY | Llama Anti-VWF Recombinant Single Domain Antibody (HPAB-1630-FY) | Inhib, ELISA | Llama VHH |
| HPAB-1631-FY | Recombinant Llama Anti-VWF Single Domain Antibody (HPAB-1631-FY) | ELISA, SPR, FC | Llama VHH |
| HPAB-1632-FY | Recombinant Llama Anti-VWF Single Domain Antibody (HPAB-1632-FY) | Inhib | Llama VHH |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-FY1936. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.