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Mouse Anti-NPC1 Recombinant Antibody (clone 8D10B6) (CAT#: VS3-XY1177)

Clone 8D10B6 is a mouse antibody, which reacts with NPC1 protein. This antibody is suitable for NPC1 detection by IHC staining.


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Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/77445/1758_F12_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human gall bladder
Figure 2 IHC staining of human gall bladder
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26618/ihc_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70132/151463_B_7_5.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70132/151514_A_7_3.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70132/151514_A_8_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70132/151514_A_7_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70132/151514_A_4_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (hTERT-HME1)
Figure 8 RNA cell line category: Cell line enhanced (hTERT-HME1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000141458-NPC1

Specifications

  • Immunogen
  • Amino acids 34-174
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • NPC1
  • Clone
  • 8D10B6
  • Applications
  • Immunohistochemistry

Product Property

  • Format
  • Liquid
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • NPC Intracellular Cholesterol Transporter 1; Niemann-Pick Disease, Type C1; Truncated Niemann-Pick C1; Niemann-Pick C1 Protein; SLC65A1; NPC

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "NPC1"

Recombinant Antibody

CAT Product Name Application Type
MOB-2561z Mouse Anti-NPC1 Recombinant Antibody (clone 39A7) WB, ELISA, FC, ICC, IF, IHC Mouse IgG2a
MOB-1716MZ Recombinant Mouse Anti-Human NPC1 Antibody ICC/IF, IHC-P, WB Mouse antibody
MRO-1096-CN Recombinant Rabbit Anti-NPC1 Monoclonal Antibody (JB87-33) WB, IF, IHC, FC Rabbit IgG
VS3-WK332 Rabbit Anti-NPC1 Recombinant Antibody (clone JB87-33) WB, ELISA Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2477 Hi-Affi™ Recombinant Rabbit Anti-NPC1 Monoclonal Antibody (DS2477AB) WB, IHC, ICC IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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