Recombinant Rabbit Anti-ABCG1 Antibody (clone R06-5B9) (CAT#: VS3-FY7)
This product is a recombinant rabbit antibody that recognizes human ABCG1 protein. It can detect a band of approximately 76 kDa (observedd molecular weight: 100 kDa).
Specific Inquiry
WB
Figure 1. Recombinant Rabbit Anti-ABCG1 Antibody (clone R06-5B9) in WB.
Western blot analysis of ABCG1 in HeLa lysates using ABCG1 Antibody.
Specifications
- Immunogen
- A synthetic peptide of human ABCG1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human ABCG1
- Species Reactivity
- Human
- Clone
- R06-5B9
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- Calculated MW: 76 kDa; Observed MW: 100 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% Glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- ATP Binding Cassette Subfamily G Member 1; ATP-Binding Cassette Transporter 8; ATP-Binding Cassette, Sub-Family G (WHITE), Member 1; ABC8; White Protein Homolog (ATP-Binding Cassette Transporter 8); ATP-Binding Cassette Transporter Member 1 Of Subfamily G; ATP-Binding Cassette Sub-Family G Member 1
- Gene ID
- 9619
- UniProt ID
- P45844
- Sequence Similarities
- Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
- Cellular Localization
- Cell membrane, Endoplasmic reticulum, Golgi apparatus, Membrane
- Post Translation Modifications
- Palmitoylation at Cys-315 seems important for trafficking from the endoplasmic reticulum.
- Protein Refseq
- NP_004906.3; NP_058198.2; NP_997057.1
- Function
- Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP (PubMed:17408620, PubMed:24576892).
The lipid efflux is ALB-dependent (PubMed:16702602).
Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol (PubMed:17408620).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ABCG1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1521z | Mouse Anti-ABCG1 Recombinant Antibody (clone 26A12) | ELISA | Mouse IgG1 |
| MRO-0017-CN | Rabbit Anti-ABCG1 Recombinant Antibody (clone CBACN-007) | WB, IF, IHC | Rabbit IgG |
| VS3-CJ965 | Rabbit Anti-ABCG1 Recombinant Antibody (VS3-CJ965) | WB, ICC, IF, IHC | Rabbit IgG |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0837MZ | Chicken Anti-ABCG1 Polyclonal IgY | WB | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0015 | Hi-Affi™ Rabbit Anti-ABCG1 Recombinant Antibody (clone DS15AB) | WB, IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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