Recombinant Mouse Anti-CD68 Antibody (clone 1B8-8F6-6H8) (CAT#: VS3-FY312)

• Immunogen
• Synthesized peptide derived from human CD68

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human CD68

• Species Reactivity
• Human

• Clone
• 1B8-8F6-6H8

• Applications
• Immunohistochemistry-Paraffin

• Conjugate
• Unconjugated

• Purification
• Affinity Chromatography Purified

• Purity
• >95%

• Format
• Liquid

• Buffer
• PBS pH 7.3, 50% Glycerol, 0.5% BSA

• Preservative
• 0.02% Sodium azide

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Immunohistochemistry: 1/100-1/500

• Alternative Names
• CD68 Molecule; CD68 Antigen; Scavenger Receptor Class D, Member 1; Macrophage Antigen CD68; GP110; Macrosialin; SCARD1; LAMP4

• Gene ID
• 968

• UniProt ID
• P34810

• Sequence Similarities
• Belongs to the LAMP family.

• Cellular Localization
• Cell membrane, Endosome, Lysosome, Membrane

• Post Translation Modifications
• N- and O-glycosylated.

• Protein Refseq
• NP_001035148.1; NP_001242.2

• Function
• Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Secondary Antibody

• 2ND-037CQ
• Chicken Anti-Mouse IgG (H&L) Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

• 2ND-041CQ
• Llama Anti-Mouse IgG (H&L) Antibody

• 2ND-042CQ
• Rabbit Anti-Mouse IgG (H&L) Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal