Recombinant Rabbit Anti-IL7 Capture Antibody (clone R08-5R8) (CAT#: VS3-WK1738)
This antibody is a rabbit recombinant antibody against human IL7. It was developed by immunization of rabbit with recombinant human IL7 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R08-5R8 and R03-5G2. The clone R08-5R8 can be used as a capture antibody in ELISA analysis to identify human IL7.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human stomach, upper
(Immunohistochemical staining of human stomach, upper shows strong cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/ihc_selected.jpg
(Immunohistochemical staining of human stomach, upper shows strong cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/ihc_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_B_7_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_B_7_5.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_7_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_7_3.jpg
Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_9_4.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_8_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_6_6.jpg
Figure 7 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_9_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19590/93504_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enhanced (CAPAN-2, HDLM-2, HEL, HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104432-IL7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104432-IL7
Specifications
- Immunogen
- Recombinant human IL7 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IL7
- Species Reactivity
- Human
- Clone
- R08-5R8
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Interleukin 7
- Gene ID
- 3574
- UniProt ID
- P13232
- Long Name
- Interleukin 7
- Sequence Similarities
- Belongs to the IL-7/IL-9 family.
- Cellular Localization
- Secreted
- Protein Refseq
- NP_000871.1
- Function
- Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis. Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG.
Recommended Products
Detection antibody
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IL7"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1626z | Mouse Anti-IL7 Recombinant Antibody (clone 27C6) | ELISA, WB, FuncS | Mouse IgG1 |
| MOB-2117MZ | Recombinant Mouse Anti-Human IL7 Antibody (clone 8528.222) | ELISA, Neut, WB | Mouse antibody |
| VS3-QX602 | Mouse Anti-IL7 Recombinant Antibody (clone AH34-12) | ELISA, WB, ICC, IHC | Mouse IgG1 |
| VS3-QX603 | Mouse Anti-IL7 Recombinant Antibody (clone AH31-34) | ELISA, WB, ICC, IHC | Mouse IgG1 |
| VS3-WK1739 | Recombinant Rabbit Anti-IL7 Detection Antibody (clone R03-5G2) | ELISA | Rabbit IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1503CQ | Mouse Anti-IL7 Recombinant Antibody (clone CBL114) | Neut, WB, IHC | Mouse IgG1 |
| NEUT-1504CQ | Mouse Anti-IL7 Recombinant Antibody (clone CBL274) | Neut, ELISA | Mouse IgG1 |
| NEUT-1505CQ | Mouse Anti-IL7 Recombinant Antibody (clone CBL415) | WB, ELISA, Neut | Mouse IgG1 |
| NEUT-1506CQ | Mouse Anti-IL7 Recombinant Antibody (clone MM0410-12T6) | WB, Neut, IHC, IHC-P | Mouse IgG1 |
| NEUT-1507CQ | Mouse Anti-IL7 Recombinant Antibody (clone NYR-hi7) | WB, ELISA, Neut | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1510CQ | Mouse Anti-Il7 Recombinant Antibody (clone M25) | Block | Mouse IgG2b |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1815 | Rabbit Anti-IL7 Recombinant Antibody (clone DS1815AB) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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