Recombinant Rabbit Anti-ITGA2B Antibody (clone R01-1C2) (CAT#: VS3-FY769)

This product is a recombinant rabbit antibody that recognizes ITGA2B. This antibody has been reported for use in Western Blot. The clone R01-1C2 is specific for human, rat ITGA2B. The antigen is synthetic peptide of human cd41.


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WB

Figure 1. Recombinant Rabbit Anti-ITGA2B Antibody (clone R01-1C2) in WB.

Figure 1. Recombinant Rabbit Anti-ITGA2B Antibody (clone R01-1C2) in WB.

Western Blot analysis of CD41 in C6, Hela lysates using Integrin α IIb antibody.


Specifications

  • Immunogen
  • Synthetic peptide of human CD41.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Rat ITGA2B
  • Species Reactivity
  • Human, Rat
  • Clone
  • R01-1C2
  • Applications
  • Western Blot
  • Conjugate
  • Unconjugated
  • MW
  • Calculated MW: 113 kDa; Observed MW: 137 kDa

Product Property

  • Purification
  • Affinity Purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
  • Preservative
  • 0.01% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000

Target

  • Alternative Names
  • Integrin Subunit Alpha 2b
  • Sequence Similarities
  • Belongs to the integrin alpha chain family.
  • Cellular Localization
  • Membrane
  • Function
  • Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "ITGA2B"

Chimeric Antibody

CAT Product Name Application Type
TAB-015-F(E) Anti-Human CD41 Recombinant Antibody Fab Fragment (Abciximab) IP, IF, FuncS, FC, Neut, ELISA, ICC Fab - G1 - kappa

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1546CQ Recombinant Mouse Anti-ITGA2B Antibody (HIP8) CyTOF, FuncS, FC, IFC, IHC, Neut IgG1, κ

Blocking Antibody

CAT Product Name Application Type
NEUT-1547CQ Recombinant Mouse Anti-ITGA2B Antibody (PAC1) FC, IP, WB, BL IgM, κ
NEUT-1548CQ Recombinant Mouse Anti-ITGA2B Antibody (A2A9/6) FC, BL, IP IgG2a, κ

Rabbit Monoclonal Antibody

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0578CQ Recombinant Mouse Anti-Human ITGA2B Antibody (1E6) ELISA IgG2a

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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