Intracellular
Cell type enhanced (Oligodendrocyte precursor cells, Late spermatids, Excitatory neurons)
Immune cell enhanced (neutrophil)
Cell line enhanced (TIME)
Homodimer. Interacts with SRC and CRK. Interacts with RAB11FIP3. Interacts with PTK2B/PYK2 (By similarity). Interacts with CTTN. Interacts (via SH3 domain) with APC. Interacts with REPS2; the interaction is direct (PubMed:12149250).
GTPase activation
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For Research Use Only. Not For Clinical Use.