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CPSF3
CPSF3 (Cleavage And Polyadenylation Specific Factor 3) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and RNA Polymerase II Transcription Termination. Gene Ontology (GO) annotations related to this gene include RNA binding and 5-3 exonuclease activity. An important paralog of this gene is INTS11.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Early spermatids, Spermatocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Interacts with CPSF2, CSTF2 and SYMPK. Interacts with TUT1; the interaction is direct and mediates the recruitment of the CPSF complex on the 3'UTR of pre-mRNAs. Interacts with WDR33. Interacts with ZC3H3 (By similarity).
Molecular function
Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, RNA-binding
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC
- Recombinant Mouse Anti-Human CPSF3 Antibody (MOB-0731MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, FC
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For Research Use Only. Not For Clinical Use.