Loading...
DACH1
This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Muller glia cells, Microglial cells, Late spermatids, Early spermatids, Horizontal cells, Excitatory neurons, Spermatocytes)
Immune cell specificity
Group enriched (eosinophil, plasmacytoid DC, NK-cell, basophil)
Cell line specificity
Cell line enhanced (AF22, HAP1, HEK93, HL-60, NB-4, SCLC-21H, SH-SY5Y, THP-1)
Interaction
Interacts with SIX1, SIX6 and EYA3. Interacts with NCOR1 and HDAC3 through its N-terminus. Interacts with SIN3A through its C-terminus (By similarity). Interacts with SMAD3 and SMAD4.
Molecular function
Activator, Developmental protein, DNA-binding, Repressor
More Types Infomation
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC, IP
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.